Screening of esophageal varices by esophageal capsule endoscopy: results of a French multicenter prospective study

Endoscopy
Sylvie Sacher-HuvelinEmmanuel Coron

Abstract

Esophageal video capsule endoscopy (ECE) is a new technique that allows examination of the esophagus using a noninvasive approach. The aim of this study was to compare ECE with esophagogastroduodenoscopy (EGD) for the diagnosis of esophageal varices in patients with cirrhosis. A total of 330 patients with cirrhosis and with no known esophageal varices were prospectively enrolled. Patients underwent ECE first, followed by EGD (gold standard). The endoscopists who performed EGD were blind to the ECE result. Patient satisfaction was assessed using a visual analog scale (maximum score 100). A total of 30 patients were excluded from the analysis because they did not undergo any endoscopic examinations. Patients (mean age 56 years; 216 male) had mainly alcoholic (45 %) or viral (27 %) cirrhosis. The diagnostic indices of ECE to diagnose and correctly stage esophageal varices were: sensitivity 76 % and 64 %, specificity 91 % and 93 %, positive predictive value 88 % and 88 %, and negative predictive value 81 % and 78 %, respectively. ECE patient satisfaction scored significantly higher than EGD (87 ± 22 vs. 58 ± 35; P < 0.0001). ECE was well tolerated and safe in patients with liver cirrhosis and suspicion of portal hypertension. The s...Continue Reading

Citations

Jun 18, 2017·Liver International : Official Journal of the International Association for the Study of the Liver·Paul CalèsUNKNOWN multicenter group VO-VCO
Feb 3, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J SongX-H Hou
Aug 7, 2018·Clinical Endoscopy·Junseok ParkJi Hyun Kim
Jul 7, 2018·Gastroenterology Research and Practice·Federico RavaioliFrancesco Azzaroli
Jun 21, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Arthur BergerUNKNOWN multicenter groups Varices œsophagiennes - Vidéo-capsule œsophagienne, Agence Nationale de Recherches sur le Sida et les Hép
Sep 22, 2020·European Journal of Gastroenterology & Hepatology·Hui XiuXueguo Sun
Mar 2, 2021·Gastrointestinal Endoscopy·Joshua MelsonDavid R Lichtenstein
Aug 1, 2021·Clinics and Research in Hepatology and Gastroenterology·Dominique ThabutChristophe Bureau

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