Screening of mild cognitive impairment in Chinese older adults--a multistage validation of the Chinese abbreviated mild cognitive impairment test

Neuroepidemiology
L C W LamW M Chan

Abstract

To develop a short cognitive test for screening mild cognitive impairment (MCI) in Hong Kong Chinese older adults. The Chinese Abbreviated MCI (CAMCI) test was developed with a multistage process. In phase 1, a short version of the cognitive test comprising a 1-min animal fluency test and a 10-min delayed word list recall was developed and tested in 578 volunteers (community-dwelling active elderly persons). In phase 2, the CAMCI test was validated in an independent and randomly recruited sample of 459 participants in a community survey. Additionally, the predictive significance of the CAMCI test was evaluated in a group of 196 subjects assessed in phase 1 for conversion to clinical dementia at 20 months' follow-up. The discriminating power of the CAMCI test in differentiating MCI from normal control (NC) and mildly demented subjects was compared with Mini Mental State Examination (MMSE) and Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) subscales. The CAMCI test was found to have high discriminating power in differentiating NC from MCI and mildly demented subjects in the phase 1 volunteer sample. The receiver operating characteristics (ROC) revealed an area under the curve (AUC) of 0.91. The ROC were further validat...Continue Reading

References

Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Oct 6, 1997·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·H F ChiuW F Chan
Jun 24, 2004·Dementia and Geriatric Cognitive Disorders·Edward Hei Lim MokHelen Fung Kum Chiu
Aug 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·E ArnáizR C Petersen
Aug 21, 2004·International Psychogeriatrics·Maddalena Bruscoli, Simon Lovestone
Aug 25, 2004·Journal of Internal Medicine·R C Petersen
Dec 2, 2004·Dementia and Geriatric Cognitive Disorders·Asmus VogelGunhild Waldemar
Dec 2, 2004·Dementia and Geriatric Cognitive Disorders·Linda C W LamCindy W C Tam
Mar 4, 2005·Journal of the American Geriatrics Society·Anthony F JormLon R White
Mar 15, 2005·Alzheimer Disease and Associated Disorders·Sandy KiladaRichard J O'Brien
Jun 25, 2005·Current Alzheimer Research·Gelin XuMinh Quach
Jul 13, 2005·Neurology·M J ChandlerC M Cullum
Aug 24, 2005·International Journal of Geriatric Psychiatry·Linda C W LamHelen F K Chiu
Dec 20, 2005·Lancet·Cleusa P FerriUNKNOWN Alzheimer's Disease International
Jan 13, 2006·Dementia and Geriatric Cognitive Disorders·A WimoB Winblad
Jan 18, 2006·International Journal of Geriatric Psychiatry·Tomohisa IshikawaHirotaka Tanabe
Apr 1, 2006·Journal of the International Neuropsychological Society : JINS·H Randall GriffithDaniel C Marson
Jun 20, 2006·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Melanie C GreenawayC Munro Cullum
Jul 14, 2006·Dementia and Geriatric Cognitive Disorders·Linda Chiu Wa LamCindy Woon Chi Tam
Jul 26, 2006·Neurology·J T TschanzUNKNOWN Cache County Investigators
Aug 9, 2006·Archives of General Psychiatry·Matthias H TabertD P Devanand
Oct 19, 2006·Dementia and Geriatric Cognitive Disorders·Sylvaine ArteroKaren Ritchie
Sep 26, 2007·International Psychogeriatrics·Linda C W LamHelen F K Chiu

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Citations

Aug 11, 2012·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Andrea R LischkaDorothy Forbes
Apr 3, 2013·International Psychogeriatrics·Candy H Y WongLinda C W Lam
Mar 27, 2013·The Gerontologist·Sheung-Tak ChengHelene H Fung
Feb 28, 2014·International Psychogeriatrics·Jianfang ChangLinda Chiu Wa Lam
Mar 26, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Shengjie ZhaoYongbo Zhao
Feb 20, 2009·International Journal of Geriatric Psychiatry·Jane A LonieKlaus P Ebmeier
Jul 16, 2014·International Psychogeriatrics·Juliana Emy YokomizoCássio Machado de Campos Bottino
Nov 2, 2012·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·M DeichselR Heinrich-Weltzien
Jul 31, 2013·Clinical Oral Investigations·Karen MeyerHüsamettin Günay
Feb 26, 2020·JAMA : the Journal of the American Medical Association·Carrie D PatnodeJennifer S Lin
Sep 19, 2019·Annals of Clinical and Translational Neurology·Hanna LuLam Linda Chiu Wa

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