PMID: 8995113Jan 1, 1997Paper

Screening of patients with a positive family history of colorectal cancer

Gastrointestinal Endoscopy Clinics of North America
R W Burt

Abstract

A positive family history is one of the most common risk factors for colon cancer. The risk varies from moderately increased when a first-degree relative has colon cancer to high when a first-degree relative is diagnosed at an age less than 50 years or there are two first-degree relatives with large bowel malignancy. The risk of colon cancer is extreme in the rare colon cancer syndromes of familial adenomatous polyposis and hereditary nonpolyposis colon cancer. The extensive characterization of familial occurrence of colon cancer has led to specific screening strategies for each of these levels of familial risk.

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Related Papers

Seminars in Oncology Nursing
M L Fitzsimmons
Revista médica de Chile
Felipe Bellolio RFrancisco López-Köstner
ANZ Journal of Surgery
Mark Omundsen, Francis F Lam
© 2022 Meta ULC. All rights reserved