Screening pregnant women for chlamydia: what are the predictors of infection?

Sexually Transmitted Infections
M Y ChenS Garland

Abstract

To determine the risk factors associated with chlamydial infection in pregnancy and the sensitivity and specificity of these when used for selective screening. A prospective, cross-sectional study of pregnant women aged 16-25 years attending four major public antenatal services across Melbourne, Australia. Between October 2006 and July 2007, women were approached consecutively and asked to complete a questionnaire and to provide a first-pass urine specimen for Chlamydia trachomatis testing using PCR. Of 1180 eligible women, 1087 were approached and 1044 (88%) consented to participate. Among the 987 women for whom a questionnaire and a definitive diagnostic assay were available, the prevalence of chlamydia was 3.2% (95% CI 1.8 to 5.9). In a multiple logistic regression model, more than one sexual partner in the past year (AOR 11.5; 95% CI 7.1 to 18.5) was associated with chlamydia infection. The use of any antibiotic within 3 months (AOR 0.2; 95% CI 0.1 to 0.6) was associated with a decreased risk of infection. Screening restricted to women who reported more than one sexual partner in the past year would have detected 44% of infections in women aged 16-25 years and would have required only 7% of women to be screened. The additio...Continue Reading

Citations

Jul 16, 2010·Archives of Gynecology and Obstetrics·Tobias M WeissenbacherIoannis Mylonas
Dec 21, 2011·Sexually Transmitted Diseases·Brooke E HootsWilliam C Miller
Jul 23, 2013·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Zhuoyang LiElizabeth A Sullivan
Apr 1, 2010·Australian and New Zealand Journal of Public Health·Nicola StephensKelly Shaw
Aug 27, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·J J OngA Hsueh
Dec 20, 2013·Scandinavian Journal of Infectious Diseases·Monique T R PereboomFrançois G Schellevis
Oct 15, 2014·Antimicrobial Agents and Chemotherapy·Nicole H T M Dukers-MuijrersChristian J P A Hoebe
Jun 9, 2017·AIDS Research and Human Retroviruses·Hamza Arshad DarAneela Javed
Feb 9, 2018·Maternal and Child Health Journal·Courtney Olson-ChenDavid N Hackney
Oct 6, 2009·Sexually Transmitted Diseases·K M O'RourkeJane S Hocking
Oct 14, 2009·Sexually Transmitted Diseases·Julia L MarcusJeffrey D Klausner
Nov 27, 2020·The Journal of Obstetrics and Gynaecology Research·Pattarawalai TalungchitPattarawan Limsiri

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