Sculpting heart valves with NFATc and VEGF

Cell
Diether Lambrechts, Peter Carmeliet

Abstract

Heart valves are of vital importance for our moment-to-moment existence, but how they form remains a mystery. In this issue of Cell, Chang et al. reveal a novel role for calcineurin, NFATs, and VEGF in valve formation. Dynamic changes in NFAT/VEGF expression in regional myocardial and endocardial fields and developmental windows orchestrate this complex process.

References

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Citations

Feb 8, 2006·Annual Review of Physiology·Patrick C H HsiehRichard T Lee
Apr 2, 2005·Cancer Cell International·S PadmaGayatri Ramakrishna
Nov 11, 2008·Free Radical Biology & Medicine·Cécile Mazière, Jean-Claude Mazière
Jul 22, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Benoit BlanchetAnne Hulin
Jan 12, 2010·Developmental Cell·Sally L Dunwoodie
Oct 9, 2012·American Journal of Human Genetics·Christine AckermanCheryl L Maslen
May 26, 2012·Circulation Research·Kyoung-Han KimPeter H Backx
Aug 14, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Masashi MuramatsuTakashi Minami
Jul 30, 2020·International Journal of Molecular Sciences·Mariantonia BraileStefania Loffredo
Jan 13, 2006·The Journal of Biological Chemistry·Sara Martínez-MartínezJuan Miguel Redondo
Mar 14, 2018·Current Opinion in Physiology·Cheng Sun, Maria I Kontaridis

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