Sealing the mitochondrial respirasome.

Molecular and Cellular Biology
Dennis R Winge

Abstract

The mitochondrial respiratory chain is organized within an array of supercomplexes that function to minimize the generation of reactive oxygen species (ROS) during electron transfer reactions. Structural models of supercomplexes are now known. Another recent advance is the discovery of non-OXPHOS complex proteins that appear to adhere to and seal the individual respiratory complexes to form stable assemblages that prevent electron leakage. This review highlights recent advances in our understanding of the structures of supercomplexes and the factors that mediate their stability.

References

Mar 28, 1998·The Journal of Biological Chemistry·H BoumansJ A Berden
Mar 26, 1998·Journal of Molecular Biology·V GuénebautT Friedrich
Apr 25, 2000·The EMBO Journal·H Schägger, K Pfeiffer
Aug 17, 2000·Biochemical and Biophysical Research Communications·S M BuddeJ A Smeitink
Jan 19, 2002·IUBMB Life·H Schägger
Mar 7, 2002·Proceedings of the National Academy of Sciences of the United States of America·Christian Lange, Carola Hunte
Feb 1, 2003·The Journal of Biological Chemistry·E C Slater
Oct 17, 2003·The Journal of Biological Chemistry·Kathy PfeifferHermann Schägger
Apr 1, 2004·Molecular Cell·Rebeca Acín-PérezJosé A Enríquez
Feb 15, 2005·Plant Physiology and Biochemistry : PPB·Holger EubelHans-Peter Braun
Feb 17, 2005·Proceedings of the National Academy of Sciences of the United States of America·Natalia V DudkinaHans-Peter Braun
Mar 23, 2006·The Journal of Biological Chemistry·Eva SchäferJanet Vonck
Jun 3, 2006·Human Molecular Genetics·Marilena D'AurelioGiovanni Manfredi
Jan 1, 1947·The Biochemical Journal·D Keilin, E F Hartree
Jun 20, 2006·Molecular and Cellular Biology·Francisca DiazCarlos T Moraes
Oct 18, 2006·The Journal of Cell Biology·Frank VogelAndreas S Reichert
Nov 15, 2006·The Journal of Biological Chemistry·Egbert J Boekema, Hans-Peter Braun
Feb 27, 2007·The Journal of Biological Chemistry·Jesco HeinemeyerRoman Kouril
Apr 4, 2007·Human Molecular Genetics·Erika Fernandez-VizarraMassimo Zeviani
Apr 25, 2007·The Journal of Biological Chemistry·Youfen LiYidong Bai
Sep 21, 2007·The EMBO Journal·David U MickPeter Rehling
May 13, 2008·Biochimica Et Biophysica Acta·Raul Covian, Bernard L Trumpower
Sep 10, 2008·The Journal of Cell Biology·Steven M ClaypoolCarla M Koehler
Nov 26, 2008·Molecular Cell·Rebeca Acín-PérezJose Antonio Enriquez
Aug 15, 2009·Archives of Biochemistry and Biophysics·Luis A GómezTory M Hagen
Sep 8, 2009·Journal of Structural Biology·T ClasonM Radermacher
May 28, 2010·Nature·Rouslan G EfremovLeonid A Sazanov
Oct 13, 2010·Biochimica Et Biophysica Acta·Nicholas J Watmough, Frank E Frerman
Jul 29, 2011·Acta Crystallographica. Section D, Biological Crystallography·Michihiro SugaShinya Yoshikawa
Aug 31, 2011·Proceedings of the National Academy of Sciences of the United States of America·Natalya V DudkinaEgbert J Boekema
Sep 13, 2011·The EMBO Journal·Thorsten AlthoffWerner Kühlbrandt
Sep 20, 2011·Biochimica Et Biophysica Acta·Masakazu MimakiMichael T Ryan
Oct 21, 2011·Proceedings of the National Academy of Sciences of the United States of America·Martin TrouillardFabrice Rappaport
Feb 22, 2012·Cell Metabolism·David Moreno-LastresCristina Ugalde

❮ Previous
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Citations

Jul 19, 2013·Molecular Biology of the Cell·Lena BöttingerThomas Becker
Feb 22, 2013·Briefings in Functional Genomics·Jesús Espada, Manel Esteller
Mar 27, 2013·Molecular and Cellular Biology·Ketki M HatleMercedes Rincon
May 28, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·D SpeijerR Szklarczyk
Apr 8, 2014·Comptes rendus biologies·Hélène Cwerman-ThibaultMarisol Corral-Debrinski
Apr 25, 2014·Proceedings of the National Academy of Sciences of the United States of America·Levi J McClellandBruce E Bowler
Oct 6, 2015·Plant, Cell & Environment·Lucila GarciaDaniel H Gonzalez
Feb 12, 2015·Biochemistry·Swati Bandi, Bruce E Bowler
Jun 21, 2014·Analytical Chemistry·A A AmoscatoV E Kagan
Nov 15, 2012·The EMBO Journal·Werner J H KoopmanPeter H G M Willems
Nov 19, 2015·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Dave Speijer
Oct 21, 2015·Frontiers in Neuroscience·Ludmila D Lukyanova, Yulia I Kirova
Sep 26, 2013·Biochimica Et Biophysica Acta·Sheree D Martin, Sean L McGee
Nov 30, 2012·Critical Reviews in Biochemistry and Molecular Biology·Ying Wang, Siegfried Hekimi
Oct 22, 2013·Biochimica Et Biophysica Acta·An S TanMichael V Berridge
Mar 12, 2013·Cell Metabolism·Wenjing XuNancy C Andrews
Feb 25, 2014·Biochimica Et Biophysica Acta·Marion BabotAlexander Galkin
Jul 20, 2016·Proceedings of the National Academy of Sciences of the United States of America·Camilla Rydström LundinPeter Brzezinski
Nov 5, 2016·Biochimica Et Biophysica Acta·Irina A SmirnovaPeter Brzezinski
Sep 30, 2016·Scientific Reports·Simone GrafPeter Brzezinski
Sep 12, 2014·Biology of Reproduction·Malena B RoneVassilios Papadopoulos
Jan 19, 2016·Journal of Inorganic Biochemistry·Matthew E GoldesBruce E Bowler
Oct 9, 2019·The Journal of Biological Chemistry·Ngoc H HoangJonathan Hosler
Nov 12, 2016·The Biochemical Journal·Dave Speijer
Apr 25, 2018·Biochemistry Research International·María Alejandra Sánchez-MuñozErick Sierra-Campos
Jul 25, 2019·Frontiers in Microbiology·Aniela B MundingerSebastian Lücker
Apr 16, 2015·The Journal of Biological Chemistry·Simanta Sarani PaulKrishnananda Chattopadhyay
Sep 7, 2018·Scientific Reports·Nayere TajielyatoEmil Alexov
Dec 9, 2020·Cells·Myriam Y HsuPaolo E Porporato
Oct 27, 2020·Current Opinion in Physiology·Yinhu WangStefan Feske
Mar 2, 2021·Journal of Bioenergetics and Biomembranes·H V Miranda-AstudilloP Cardol
Feb 23, 2021·PeerJ·Ceyhun BereketogluAjay Pradhan

❮ Previous
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