Search for human herpesvirus 6, human cytomegalovirus and varicella zoster virus DNA in recurrent aphthous stomatitis tissue

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
F GhodratnamaD Wray

Abstract

In the present study, the involvement of human herpesvirus 6 (HHV-6), human cytomegalovirus (HCMV) and varicella zoster virus (VZV) in the aetiology of recurrent aphthous stomatitis (RAS) was investigated using the polymerase chain reaction (PCR). Biopsies from 21 RAS patients were analysed, and 20 oral lichen planus (OLP) and 13 normal biopsies were tested as controls. HHV-6-DNA was detected in six of the RAS samples whereas VZV-DNA and HCMV-DNA were not detected in any RAS samples. In the OLP samples, four biopsies were positive for HHV-6-DNA and two were positive for HCMV-DNA. One sample from this group was positive for both HHV-6-DNA and HCMV-DNA. VZV-DNA was not found in any RAS or OLP biopsies. No viral DNA was present in any normal control biopsies. These results do not support an aetiological role for HCMV and VZV in RAS, although the possible involvement of HHV-6 cannot be excluded.

References

Dec 1, 1977·Archives of Dermatology·A S Russell, J Schlaut
Apr 1, 1992·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A PedersenB Kenrad
Feb 1, 1990·Oral Surgery, Oral Medicine, and Oral Pathology·R LandesbergR Insel
Sep 1, 1990·Journal of Medical Virology·R F JarrettD E Onions
Nov 1, 1990·Journal of Medical Virology·S KidoK Yamanishi
Jan 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A PedersenJ P Stenvang
Jan 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·C Scully, S Porter
Jun 1, 1986·The Journal of Dermatology·A SunH W Kwan
Jan 1, 1995·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·R Leimola-VirtanenS Syrjänen
Sep 1, 1993·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H C Schønheyder, G Pedersen
Feb 1, 1993·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A Pedersen, A Hornsleth
May 1, 1996·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A SunC P Chiang

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Citations

Feb 24, 2001·Quintessence International·J A ShipM Sarmadi
Oct 9, 2002·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Lene Nielsen, Bent Faber Vestergaard
Feb 16, 2000·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·S L BriceW L Weston
Dec 22, 2004·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Yelda KarincaogluMetin Genc
Oct 29, 2003·Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology·Cathal OFlathartaMohamed J E M F Mabruk
Nov 13, 2001·American Journal of Clinical Dermatology·C ScullyM Carrozzo
Sep 26, 2003·American Journal of Clinical Dermatology·A Ross Kerr, Jonathan A Ship
Mar 26, 2003·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Júnia Maria Netto VictóriaRicardo Santiago Gomez
May 16, 2007·Australian Dental Journal·V Vucicevic Boras, N W Savage
Jun 15, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Giovanni LodiKobkan Thongprasom
Aug 4, 2004·International Journal of Oral and Maxillofacial Surgery·S S NatahR Häyrinen-Immonen
Jan 28, 1999·Journal of the American Academy of Dermatology·J V Ghate, J L Jorizzo
Nov 30, 2004·Dental Clinics of North America·Sunday O Akintoye, Martin S Greenberg
Jan 5, 2006·Oral Diseases·S JurgeS R Porter
Aug 30, 2003·HIV Clinician·Kishore Shetty
Aug 10, 2001·Journal of the European Academy of Dermatology and Venereology : JEADV·M Onder, M A Gürer
Apr 21, 2001·The Journal of Clinical Pediatric Dentistry·A KolokotronisA Matiais
Jan 16, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·F GhodratnamaJ Bagg

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