Seasonal changes in mite allergen (Der I and Der II) concentrations in Japanese homes

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
H MiyazawaT Shida

Abstract

There has been no report on seasonal changes in Der II allergen in floor and bedding dust. The purpose of this study was to examine the extent of seasonal changes in Der I and Der II allergens in the floor and bedding dust found in houses. We measured the absolute concentrations of mite allergens in dust collected monthly for 1 year from both the floors and bedding of eight houses in Tokyo. Dust samples were obtained from eight families without regard to their allergy histories. The concentrations of the Der p I, Der f I, and Der II allergens were measured by fluorometric sandwich ELISA. We found seasonal changes in the concentrations of these mite allergens. The highest concentrations of Der I (Der p I plus Der f I) and Der II (Der p II plus Der f II) were present from August to October, and the lowest ones from March to April. In floor dust, the mean highest concentrations of Der I and Der II (35.0 and 20.2 microgram of fine dust) were sevenfold and fivefold respectively, times the mean lowest concentrations. In bedding dust, the mean highest concentrations of Der I and Der II (51.3 and 29.6 microgram/g of fine dust) each were fourfold times the mean lowest concentrations. The patterns of seasonal changes in Der II in floor a...Continue Reading

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Citations

Feb 19, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Shin-ichi ToyabeKouhei Akazawa
Mar 17, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·J A BellantiJ A Genuardi
Jun 1, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D H NahmC S Hong
Nov 28, 2014·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Tyra Bryant-StephensGary Klein
Jul 25, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K WickensJ Crane
Sep 5, 2014·Expert Review of Vaccines·Philippe Moingeon
Aug 28, 2016·Respiratory Investigation·Masaya TakemuraMotonari Fukui
Nov 28, 2012·International Archives of Allergy and Immunology·D HervásL García-Marcos

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