Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma)

The American Journal of Dermatopathology
Dmitry V KazakovMichal Michal

Abstract

We describe 11 poroid neoplasms with sebaceous differentiation, including a metaplastic (sarcomatoid) carcinoma arising in association with an apocrine poroma. Six lesions had the silhouette of a classical poroma, 3 of poroid hidradenoma and 1 of dermal duct tumor. In all cases, sebaceous differentiation was identified as clustered or solitary, mature sebocytes occurring mainly at the periphery of intradermal cellular aggregations, accompanied by sebaceous ducts. In one poroma, clusters of sebocytes were seen within intradermal aggregates and intraepidermally. In 1 of the 3 poroid hidradenomas, the eosinophilic cuticle lining the cyst was crenulated in foci associated with sebocytes. In none of the cases were there signs of follicular differentiation. One poroma, in addition to sebaceous differentiation, showed decapitation secretion in some ductular structures. The single carcinoma was an ulcerated oval to spindle cell neoplasm surrounded laterally by the residuum of a poroma containing groups of sebocytes. The epithelial islands of the poroma were prominently keratinized and blended gradually with the pleomorphic cells of the metaplastic carcinoma that immunohistochemically stained focally for cytokeratins and simultaneously ...Continue Reading

References

Jun 1, 1992·The American Journal of Dermatopathology·L RequenaD J Santa Cruz
Apr 1, 1991·Journal of Cutaneous Pathology·F SakamotoY Sato
Aug 1, 1990·The American Journal of Dermatopathology·R E NakhlehM R Wick
Oct 1, 1989·The American Journal of Dermatopathology·H M Hassab-el-NabyA B Ackerman
Aug 1, 1988·The American Journal of Dermatopathology·M T Zaim
Dec 1, 1984·The American Journal of Dermatopathology·D HanauG Laplanche
Dec 1, 1982·The British Journal of Dermatology·M ShawM M Black
Feb 1, 1983·Archives of Dermatology·A H MehreganH Rahbari
Apr 1, 1993·The American Journal of Dermatopathology·W WeyersW B Schill
Feb 1, 1996·The American Journal of Dermatopathology·J D HarvellP E LeBoit
Apr 1, 1996·The American Journal of Dermatopathology·T H McCalmont
Aug 1, 1997·The American Journal of Dermatopathology·R M PujolW P Su
Oct 28, 1998·The American Journal of Dermatopathology·R GianottiE Alessi
Oct 28, 1998·The American Journal of Dermatopathology·P J Heenan
Feb 23, 1999·The American Journal of Dermatopathology·P A GrobenW L White
Jun 28, 2000·The American Journal of Dermatopathology·N H LeeS K Ahn
Feb 13, 2001·Journal of Cutaneous Pathology·H KamiyaY Kitajima
Feb 15, 2001·The American Journal of Dermatopathology·N Misago, Y Narisawa
Jun 8, 2001·The American Journal of Surgical Pathology·A RobsonE Calonje
Jan 23, 2002·The American Journal of Dermatopathology·Angel Santos-BrizFernando López-Ríos
Jul 27, 2002·The American Journal of Dermatopathology·Noriyuki MisagoYutaka Narisawa
Jul 14, 2004·The American Journal of Dermatopathology·Dmitry V KazakovMichal Michal
Nov 12, 2005·Archives of Dermatological Research·Han-Nan LiuCheng-Hung Huang
Apr 21, 2006·The American Journal of Dermatopathology·Dmitry V KazakovMichal Michal
Jun 27, 2006·International Journal of Dermatology·Chih-Chiang ChenHan-Nan Liu
Jan 12, 2007·Journal of Cutaneous Pathology·Seng Geok Nicholas GohEduardo Calonje
Jan 24, 2008·The American Journal of Dermatopathology·Dmitry V KazakovEduardo Calonje

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Citations

May 1, 2010·The American Journal of Dermatopathology·Angel Fernandez-Flores
May 24, 2011·Applied Immunohistochemistry & Molecular Morphology : AIMM·Angel Fernandez-Flores
Oct 25, 2013·Indian Journal of Pathology & Microbiology·Yong Huang
Mar 4, 2017·The Journal of Dermatology·Shin-Ichi Ansai
Jun 17, 2016·The American Journal of Dermatopathology·Rafael Parra-MedinaSamuel D Morales
Oct 21, 2016·The American Journal of Dermatopathology·Ryan C RomanoRichard W Nicholas
Apr 25, 2017·Journal of Cutaneous Pathology·Gauri Panse, Antonio Subtil
Apr 4, 2017·The American Journal of Surgical Pathology·Liubov KyrpychovaDmitry V Kazakov
Nov 3, 2017·The American Journal of Dermatopathology·Marcelo G HorensteinJack Jacob
Jun 14, 2018·The Australasian Journal of Dermatology·Ho Jeong ShinMi Woo Lee
May 22, 2018·Journal of Cutaneous Pathology·Robert MillerJames Chan
Jan 3, 2018·The American Journal of Dermatopathology·Renato PazziniRicardo S Macarenco
Jun 16, 2010·The Australasian Journal of Dermatology·Yuta KurashigeRyoji Tsuboi
May 7, 2016·Applied Immunohistochemistry & Molecular Morphology : AIMM·Angel Fernandez-Flores, David S Cassarino
Aug 1, 2020·Journal of Cutaneous Pathology·Mar Llamas-VelascoDavid Samuel Cassarino
May 6, 2015·The American Journal of Dermatopathology·Mary D LeDavid S Cassarino
Aug 14, 2015·Journal of Cutaneous Pathology·Tadao NakazawaRyohei Katoh
Feb 10, 2021·The Journal of Dermatology·Kohei OgawaHideo Asada
Mar 20, 2021·The American Journal of Surgical Pathology·Nicolas MacagnoMaxime Battistella

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