Second Generation Drug-Eluting Stents for Endovascular Treatment of Ostial Vertebral Artery Stenosis: A Single Center Experience

Frontiers in Neurology
Santiago Ortega-GutierrezEdgar A Samaniego

Abstract

Objective: To report a single-center experience using drug-eluting balloon mounted stents (DES) for endovascular treatment of atherosclerotic ostial vertebral artery stenosis (OVAS). Background: Posterior circulation is affected in up to 25% of strokes, 20% of them resulting from atherosclerotic OVAS. The optimal management of symptomatic OVAS remains controversial. DES have been introduced to improve restenosis rates. Methods: We retrospectively analyzed prospectively collected data from patients with dominant OVAS who underwent endovascular treatment with second-generation DES placement. Patient demographics, clinical presentation, comorbidities, stenosis severity, stent features, technical success, complications, and imaging follow-up were assessed. Results: Thirty patients were treated, predominantly male (86.6%). Sixteen patients presented with an acute stroke or TIA and fourteen were treated on an elective basis due to symptomatic chronic stenosis and contralateral occlusion. Comorbidities included hyperlipidemia (83%), hypertension (70%) and prior stroke (63.3%). Mean ostial stenosis at presentation was 80 ± 14.8%. Twenty-one patients had contralateral VA involvement. DES deployment was technically successful in all pati...Continue Reading

References

Dec 31, 2002·Journal of the American College of Cardiology·Donald E CutlipRichard E Kuntz
Aug 29, 2003·Neurosurgery·Felipe C AlbuquerqueCameron G McDougall
Jun 24, 2005·The New England Journal of Medicine·Sean I Savitz, Louis R Caplan
Oct 5, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Xinpu ChenJianmin Liu
May 3, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Marc A LazzaroOsama O Zaidat
Jun 28, 2011·Stroke; a Journal of Cerebral Circulation·Aaron N StaymanRishi Gupta
Jul 7, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Afshin Borhani HaghighiOsama O Zaidat
Sep 9, 2011·The New England Journal of Medicine·Marc I ChimowitzUNKNOWN SAMMPRIS Trial Investigators
Dec 31, 2011·Journal of Vascular Surgery·George A AntoniouJ Vincent Smyth
Jan 4, 2012·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Randall C EdgellTudor Jovin
May 2, 2012·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Lipo SongJian Zhang
Jan 18, 2013·The New England Journal of Medicine·Giulio G Stefanini, David R Holmes
Aug 5, 2014·JACC. Cardiovascular Interventions·Lisette Okkels JensenUNKNOWN Scandinavian Organization for Randomized Trials With Clinical Outcome SORT OUT IV Investigators
Oct 8, 2014·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Nicolas LangwieserTareq Ibrahim
Apr 11, 2015·Circulation. Cardiovascular Interventions·Raffaele PiccoloStephan Windecker
Jul 17, 2015·Journal of Neurointerventional Surgery·Vivek H TankChirag D Gandhi
Feb 20, 2016·Journal of the American College of Cardiology·Lisette Okkels JensenUNKNOWN SORT OUT IV Investigators

❮ Previous
Next ❯

Citations

Dec 29, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Mostafa JafariAfshin A Divani

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation
dissection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
Aysun Erbahceci SalikBatuhan Kara
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Xinpu ChenJianmin Liu
Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
E BroussalisM Killer-Oberpfalzer
© 2021 Meta ULC. All rights reserved