PMID: 12770422Jun 1, 1997Paper

Second messenger-controlled membrane conductance in locust (Locusta migratoria) olfactory neurons

Journal of Insect Physiology
H BreerJ W. Wegener

Abstract

The membrane conductance of olfactory neurons of Locusta migratoria was examined using the whole-cell configuration of the patch-clamp technique. Intracellular application of the second messenger inositol 1,4,5 trisphosphate (IP(3)) via a dual pipette technique elicited a clear increase in the membrane conductance. The IP(3)-induced conductance increased due to a rise in the extracellular concentration of calcium from 100&mgr;M to 4mM. Micromolar concentrations of ruthenium red partially blocked the IP(3)-induced increase in membrane conductance. Stimulating olfactory neurons with odour (hexenoic acid) resulted in an increase in the membrane conductance partially similar to that mediated IP(3). These findings suggest that stimulation with appropriate odours as well as intracellular application of IP(3) activate the same calcium-permeable ion channels in the plasma membrane of insect olfactory neurons.

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Citations

Mar 29, 2002·Journal of Neurobiology·Masayuki Koganezawa, Ichiro Shimada
Oct 23, 1998·Invertebrate Neuroscience : in·J KriegerH Breer
Jul 5, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Monika Stengl, Nico W Funk
Sep 25, 2002·The European Journal of Neuroscience·Jürgen KriegerHeinz Breer
Apr 24, 2007·Journal of Insect Physiology·J Joe HullShogo Matsumoto
Aug 8, 2008·Journal of Neurophysiology·Steffi Krannich, Monika Stengl
Mar 26, 2003·The Journal of Experimental Biology·Jan DolzerMonika Stengl
Oct 26, 1999·Science·J Krieger, H Breer

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