PMID: 18411111Jan 1, 1990Paper

Second messengers of insulin action

Trends in Endocrinology and Metabolism : TEM
A R Saltiel

Abstract

The molecular events involved in coupling the insulin receptor to the regulation of cellular metabolism remain unknown. Recent studies indicate that some of insulin's actions may be mediated by a novel oligosaccharide. This molecule is generated in cells by the insulin-dependent hydrolysis of a novel membrane glycolipid, termed a glycosyl-phosphatidylinositol. This glycolipid is structurally similar to a newly described protein anchor. The evaluation of the hormonal regulation of this new glycolipid may yield information on a new mechanism of signal transduction.

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Citations

Mar 1, 1993·The Journal of Steroid Biochemistry and Molecular Biology·J E Nestler
Feb 1, 1992·The International Journal of Biochemistry·B AlmåsJ E Hesketh
Jan 23, 1998·The International Journal of Biochemistry & Cell Biology·M CurtoM T Rinaudo
Oct 1, 1995·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·R J Marles, N R Farnsworth
Dec 9, 2008·Metabolism: Clinical and Experimental·Marie-Claude VilleneuveJean-Patrice Baillargeon
Mar 19, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·F CorradoA Di Benedetto
Sep 21, 2002·Molecular and Cellular Endocrinology·Christine FilippisJoseph Proietto
Nov 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·A VølundJ Schlichtkrull

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