PMID: 2509712Aug 20, 1989Paper

Second-order repeats in Xenopus laevis finger proteins

Journal of Molecular Biology
W NietfeldW Knöchel

Abstract

The primary structure of 342 finger repeats encoded in 42 different cDNA clones isolated from Xenopus laevis oocyte and gastrula cDNA libraries has been determined. Comparative sequence analysis of the predicted protein sequences results in a consensus repeat sequence that has an extended conserved segment of 16 amino acid residues, including the evolutionary conserved H/C link element, connected to a highly variable segment that is located in the finger loop region. Groups of tandem finger repeats are found to be organized in distinct higher-order structural units, with a pair of mutually distinct fingers being the most frequently observed second-order repeat unit. Structural features observed are discussed in respect to existing models for Zn finger structure and function.

References

Mar 1, 1988·Molecular and Cellular Biology·P ChavrierP Charnay
Apr 1, 1988·Molecular and Cellular Biology·K E VranaD D Brown
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·J S CulpR P Ricciardi
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Jun 13, 1966·Biochemical and Biophysical Research Communications·D T Denhardt
Jan 1, 1984·Annual Review of Biochemistry·C O Pabo, R T Sauer

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Citations

Jan 12, 1995·Molecular and Cellular Biochemistry·B Klocke, W Knöchel
May 1, 1989·Cell Differentiation and Development : the Official Journal of the International Society of Developmental Biologists·W Knöchel, H Tiedemann
Nov 1, 1991·Mechanisms of Development·T el-Baradi, T Pieler
Mar 20, 2003·Academic Radiology·J Shannon SwanDennis M Heisey
Oct 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M KochoyanM A Weiss
Nov 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·P BrayI B Dawid
Nov 13, 1992·Cell·O TheunissenT Pieler
Jun 19, 1990·Biochemistry·M A WeissH T Keutmann
Jan 13, 1992·FEBS Letters·R J Mortishire-SmithP E Wright
Jun 1, 1993·Trends in Biochemical Sciences·T Pieler, O Theunissen

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