PMID: 8959675Nov 1, 1996Paper

Second primary lung cancer in Flanders: frequency, clinical presentation, treatment and prognosis

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
J Van MeerbeeckM Uydebrouck

Abstract

Patient and tumour characteristics of 23 patients presenting with a second primary lung cancer were analysed and compared with 534 patients with radically resected stage 1 non-small cell lung cancer (NSCLC). None of these characteristics is associated with a higher occurrence rate for second primary lung cancer. Prognosis in the latter patients is significantly worse than after resection of a 'solitary' NSCLC: the median survival time (MST) after resection of the first tumour is 50 months; after diagnosis of the second tumour only 14 months. Surgically retreated patients have a prognosis that is similar to that after resection of a 'solitary' NSCLC. No separate independent prognostic factors responsible for this survival difference could be isolated. Squamous histology and central location are associated with a longer recurrence free survival time. We conclude that the occurrence of a second primary lung cancer can not be predicted based on patient or tumour characteristics and that only surgical retreatment offers a chance of long survival in these patients.

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Citations

Sep 27, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Steven M KellerUNKNOWN Eastern Cooperative Oncology Group
Sep 25, 1998·Journal of the National Cancer Institute·B E Johnson
Jul 20, 2014·The Annals of Thoracic Surgery·R Taylor RipleyJames Huang
Apr 13, 2006·Chest·Hiroshi Sugimura, Ping Yang
Mar 6, 2012·The Annals of Thoracic Surgery·Chiaki EndoTakashi Kondo
Aug 2, 2015·The Journal of Surgical Research·Leah M BackhusSteven B Zeliadt
Oct 8, 2003·The Annals of Thoracic Surgery·David RiceJack Roth
Mar 6, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Frank C DetterbeckUNKNOWN Multiple Pulmonary Sites Workgroup
Sep 27, 2005·The Annals of Thoracic Surgery·Michael S KentRobert J Korst
Jul 1, 2005·Seminars in Oncology·Noel R Wardwell, Pierre P Massion
Jun 12, 2018·Indian Journal of Surgical Oncology·Taiji KuwataFumihiro Tanaka
Feb 22, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B JeremicG Radosavljevic-Asic

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