PMID: 9420843Jan 1, 1995Paper

Second-trimester placental volumes predict birth weight at term

Journal of the Society for Gynecologic Investigation
J F ClappJ R Crass

Abstract

To test the hypothesis that second-trimester placental growth is a major determinant of size at birth in healthy, active women. Three serial measurements of fetal morphometry and placental volume were obtained between the 14th and 26th weeks of an accurately dated singleton pregnancy in 40 subjects. Second-trimester placental volumes were variable, increasing from (mean +/- standard deviation) 130 +/- 35 to 248 +/- 67 and to 375 +/- 92 cm3 at 16, 20, and 24 weeks, with an average growth rate of 31 +/- 8 cm3/weeks. At delivery, fresh placental volumes and birth weights were also variable, ranging between 304-823 cm3 and 2.6-4.4 kg, respectively. Significant correlations (r > 0.79) were present between second-trimester placental volume or growth rate and placental volume at delivery and birth weight, corrected for gestational age and infant sex. However, correlations between second-trimester fetal biometry and both corrected birth weight and birth weight percentile were poor (r < 0.45). Second-trimester placental volumes and growth rates are good predictors of size at birth in healthy, active women. We speculate that this technique may have real value as an early screening tool to identify cases at risk of anomalous third-trimest...Continue Reading

Citations

Aug 17, 2001·Obstetrics and Gynecology·M ThameT E Forrester
Mar 29, 2008·Metabolic Syndrome and Related Disorders·James F Clapp Iii, Beth Lopez
Dec 24, 1997·Acta Paediatrica. Supplement·G PardiI Cetin
Feb 21, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·J-C BecherB Wyatt
Feb 20, 2009·Prenatal Diagnosis·Winnie W I PangRossa W K Chiu
Sep 20, 2011·Journal of Magnetic Resonance Imaging : JMRI·Iris E DerwigKypros H Nicolaides
Sep 19, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·R M JeffreysJ F Clapp
Feb 29, 2000·American Journal of Obstetrics and Gynecology·A S KinareD T Howe
Jun 24, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hayley S QuantNadav Schwartz

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