Secondary ion images of the developing rat brain

Journal of the American Society for Mass Spectrometry
P J ToddC A McCandlish

Abstract

Secondary ion images were obtained from sections of rat brain over a 21 day postnatal period, using the intensity of m/z 184, phosphocholine. When compared with corresponding optical images of similar, but stained sections from the same animal, the secondary ion images appear to reflect less developed brains. During development, myelination occurs after axon extension. Apparently, myelination obscures the source of secondary m/z 184, phosphatidylcholine, from the analyzing ion probe; absenting myelination, secondary ion images show no physiological features.

References

Feb 1, 1979·The Biochemical Journal·A J Crang, M G Rumsby
Oct 1, 1985·Scientific American·M S Bretscher
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Oct 1, 1985·Scientific American·S Tonegawa
Sep 1, 1997·Analytical Chemistry·P J ToddC A McCandlish
Mar 3, 1998·Neurochemical Research·M R PrasadW R Markesbery
Mar 4, 2000·Journal of the American Society for Mass Spectrometry·C A McCandlishP J Todd
Dec 26, 2001·Chemical Reviews·M L Pacholski, N Winograd
Sep 5, 1986·Science·J G Hildebrand
Nov 1, 1995·Journal of the American Society for Mass Spectrometry·J M McMahonP J Todd
Sep 1, 1991·Journal of the American Society for Mass Spectrometry·C C GrimmP J Todd

❮ Previous
Next ❯

Citations

Jun 1, 2005·Journal of the American Society for Mass Spectrometry·Anna C CreceliusBobby Bodenheimer
Mar 28, 2013·ACS Chemical Neuroscience·Jörg HanriederAndrew G Ewing
Apr 29, 2010·Chemical Reviews·Kamila Chughtai, Ron M A Heeren
Jun 5, 2007·Nature Protocols·A F Maarten AltelaarRon M A Heeren
Jul 11, 2007·Journal of Mass Spectrometry : JMS·John A McLeanRichard M Caprioli
Aug 21, 2008·Proteomics·Eric B MonroeJonathan V Sweedler
May 10, 2005·Journal of Mass Spectrometry : JMS

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

© 2022 Meta ULC. All rights reserved