Secondary Prevention Three and Six Years after Stroke Using the French National Insurance Healthcare System Database

European Neurology
Laura MechtouffAnne-Marie Schott

Abstract

Secondary prevention is inadequate in the first 2 years after stroke but what happens after that is less documented. The aim of this study was to assess the use and the adherence to preventive drugs 3 and 6 years after experiencing a transient ischemic attack (TIA) or an ischemic stroke (IS). The population study was from the AVC69 cohort (IS or TIA admitted in an emergency or stroke unit in the Rhône area, France, for an IS or a TIA during a 7-month period). Medication use was defined as ≥1 purchase during the studied year and adherence as Continuous Measure of Medication Acquisition ≥0.8 using the French medical insurance health care funding database. The study population consisted of 210 patients at 3 years and 163 patients at 6 years. Medication use at 3 and 6 years was, respectively, 80.9 and 79.8% for antithrombotics, 69.1 and 66.3% for antihypertensives, 60.5 and 55.2% for statins and 48.6 and 46.6% for optimal treatment defined as the treatment achieved by the use of the 3 drugs. Adherence to each class was good at 3 years and tends to decrease at 6 years. More than one patient out of 2 do not use the optimal preventive treatment.

References

May 24, 2000·Neurology·R G HollowayS R Rush
Aug 4, 2001·Stroke; a Journal of Cerebral Circulation·T SappokH C Koennecke
Aug 11, 2006·The New England Journal of Medicine·Pierre AmarencoUNKNOWN Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators
Aug 9, 2008·Stroke; a Journal of Cerebral Circulation·Björn WettermarkMia von Euler
Feb 26, 2009·Pharmacoepidemiology and Drug Safety·Pernelle NoizeAnnie Fourrier-Réglat
Jan 16, 2010·Stroke; a Journal of Cerebral Circulation·Eva-Lotta GladerMichael Lundberg
Feb 4, 2010·Pharmacoepidemiology and Drug Safety·Karin Martin-Latry, Bernard Bégaud
May 29, 2010·Stroke; a Journal of Cerebral Circulation·Nadia A KhanMoira Kapral
Aug 11, 2010·Archives of Neurology·Cheryl D BushnellUNKNOWN Adherence Evaluation After Ischemic Stroke–Longitudinal Investigators
Jan 5, 2011·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Ronan O'CarrollMartin Dennis
Sep 9, 2011·Neurology·C D BushnellUNKNOWN AVAIL Investigators
Nov 10, 2011·Pharmacoepidemiology and Drug Safety·Maria SjölanderEva-Lotta Glader
Sep 20, 2012·International Journal of Stroke : Official Journal of the International Stroke Society·Sylvie Porthault-ChatardAnne-Marie Schott
Nov 16, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Yannick BéjotYves Cottin
Dec 12, 2012·Stroke; a Journal of Cerebral Circulation·Carina HohmannRoland Radziwill
Jan 5, 2013·Journal of General Internal Medicine·Ian M KronishCarol R Horowitz
Jun 6, 2013·Stroke; a Journal of Cerebral Circulation·Julie HaesebaertAnne-Marie Schott
Jun 27, 2013·The American Journal of Medicine·Dharam J KumbhaniUNKNOWN REduction of Atherothrombosis for Continued Health Registry Investigators
Dec 18, 2013·Stroke; a Journal of Cerebral Circulation·Amanda G ThriftRoger G Evans
May 3, 2014·Stroke; a Journal of Cerebral Circulation·Walter N KernanUNKNOWN American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and
Dec 11, 2014·International Journal of Stroke : Official Journal of the International Stroke Society·Priya ParmarUNKNOWN Stroke RiskometerTM Collaboration Writing Group
Apr 18, 2015·Stroke; a Journal of Cerebral Circulation·Valery L FeiginUNKNOWN RIBURST Study Collaboration Writing Group
Jul 23, 2016·Nature Reviews. Neurology·Valery L FeiginGeorge A Mensah

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