PMID: 6171773Oct 10, 1981Paper

Secondary structure formation during RNA synthesis

Nucleic Acids Research
F R Kramer, D R Mills

Abstract

We observed the secondary structures that formed in an RNA molecule during its synthesis. Some of the secondary structures seen in nascent chains were observed to form, then to dissociate in favor of an alternative structure, and then to reform, as chain growth continued. The results show that secondary structures in an RNA molecule are in a state of dynamic equilibrium, and that the extension of a sequence by chain growth, or the reduction of a sequence by processing, may result in significant changes in the secondary structures that are present.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Nov 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·F R Kramer, D R Mills
May 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D R Mills, F R Kramer
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Aug 1, 1977·Nucleic Acids Research·H Donis-KellerW Gilbert
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Oct 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·D L KacianS Spiegelman
Jun 1, 1973·Science·D R MillsS Spiegelman
Aug 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·I Haruna, S Spiegelman

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Citations

Nov 1, 1987·Molecular & General Genetics : MGG·K R Kearney, M Nomura
Jan 1, 1985·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·N R Pace, T L Marsh
Sep 21, 2007·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Alexander V Yakhnin
Oct 5, 2007·Journal of Biosciences·Dhananjay BhattacharyyaBhabdyuti Sinha
Nov 30, 2002·Biochimie·Jord H A Nagel, Cornelis W A Pleij
Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·T R Cech
May 28, 1996·Proceedings of the National Academy of Sciences of the United States of America·S TyagiF R Kramer
Jan 15, 2000·Journal of Biomolecular Structure & Dynamics·J C Wu, B A Shapiro
Dec 9, 1985·Nucleic Acids Research·S E LaFlammeD R Mills
Dec 9, 1988·Nucleic Acids Research·C D LiarakosR A Kopper
Dec 21, 2006·Nucleic Acids Research·A XayaphoummineH Isambert
Apr 15, 2006·Nucleic Acids Research·Ruud J W Schoemaker, Alexander P Gultyaev
Mar 21, 2013·Nucleic Acids Research·Jeff R Proctor, Irmtraud M Meyer
Apr 30, 2013·Nucleic Acids Research·Jing Yun A ZhuIrmtraud M Meyer
Jan 1, 1997·Annual Review of Biophysics and Biomolecular Structure·P Brion, E Westhof
Aug 10, 2004·BMC Molecular Biology·Irmtraud M Meyer, István Miklós
Oct 18, 2013·RNA·Daniel LaiIrmtraud M Meyer
May 21, 2003·RNA·Susan L Heilman-Miller, Sarah A Woodson
Feb 24, 2012·PLoS Computational Biology·Giulio QuartaTamar Schlick
Dec 10, 2013·Molecular Therapy : the Journal of the American Society of Gene Therapy·Peng Wen PaoZacharias Aloysius Dwipramono
Jul 1, 2009·Methods : a Companion to Methods in Enzymology·Hervé Isambert
Dec 15, 1983·Journal of Molecular Biology·E A MieleF R Kramer
Sep 5, 2006·Journal of Molecular Biology·Christopher I JonesPaul F Agris
Jan 10, 2012·The Journal of Chemical Physics·Peinan ZhaoShi-Jie Chen
Jan 13, 2015·The Journal of Chemical Physics·Sha GongWenbing Zhang
Nov 1, 2016·Nature Structural & Molecular Biology·Kyle E WattersJulius B Lucks
Jan 12, 2016·PLoS Genetics·Simona CugusiJohn C Lucchesi
Feb 20, 1989·Journal of Molecular Biology·D R MillsB D Binderow

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