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Secretase-mediated cell surface shedding of the angiotensin-converting enzyme

Protein and Peptide Letters

Nov 17, 2004

Edward T ParkinN M Hooper

PMID: 15544563

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Abstract

Angiotensin-converting enzyme (ACE) is an example of a membrane-bound protein, which is shed from the cell surface in a soluble form by a post-translational proteolytic cleavage event involving a secretase. The secretase cleavage site in somatic ACE has been mapped to Arg-1203/Ser-1204,...read more

Mentioned in this Paper

I-476 BACE isoform, human
Aspartic Acid Endopeptidases
Post-Translational Protein Processing
Tertiary Protein Structure
Cytokinesis of the Fertilized Ovum
Endopeptidases
Proteolytic Enzyme
Soluble
Cell Surface
Substrate Specificity
Paper Details
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Secretase-mediated cell surface shedding of the angiotensin-converting enzyme

Protein and Peptide Letters

Nov 17, 2004

Edward T ParkinN M Hooper

PMID: 15544563

DOI:

Abstract

Angiotensin-converting enzyme (ACE) is an example of a membrane-bound protein, which is shed from the cell surface in a soluble form by a post-translational proteolytic cleavage event involving a secretase. The secretase cleavage site in somatic ACE has been mapped to Arg-1203/Ser-1204,...read more

Mentioned in this Paper

I-476 BACE isoform, human
Aspartic Acid Endopeptidases
Post-Translational Protein Processing
Tertiary Protein Structure
Cytokinesis of the Fertilized Ovum
Endopeptidases
Proteolytic Enzyme
Soluble
Cell Surface
Substrate Specificity

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Paper Details
References
  • References
  • Citations18
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations18
12

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