PMID: 15239042Jul 9, 2004Paper

Secreting vagal paraganglioma

American Journal of Otolaryngology
Jan C GroblewskiRicardo L Carrau

Abstract

Paragangliomas are rare tumors that derive from neural crest tissue. Vagal paragangliomas account for only 3% of all head and neck paragangliomas. Patients with vagal paragangliomas typically present with an asymptomatic neck mass and, less frequently, with cranial neuropathies. It is estimated that only 1% to 3% of all head and neck paragangliomas secrete catecholamines. The incidence of secreting vagal paragangliomas is even smaller. The diagnosis of a secreting paraganglioma involves the use of a screening test for serum catecholamines and a 24-hour urinary test for catecholamine metabolites. The identification and staging of these tumors can be performed through the use of MRI and/or CT scans and an octreotide scintigraphy. The mainstay treatment is surgical extirpation; however, preoperative medical blockade is critical to avoid a hypertensive crisis intra-operatively. We present two illustrative cases of secreting vagal paragangliomas involving a complex diagnostic and therapeutic algorithm.

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Citations

Feb 11, 2014·Annals of Vascular Surgery·Laura A PetersonPatrick S Vaccaro
May 16, 2008·Surgical Oncology·Francisco S LozanoAngel Muñoz
Nov 26, 2015·Journal of Maxillofacial and Oral Surgery·Carlos Moreno-GarcíaFlorencio Monje
Jul 20, 2021·Endocrinology, Diabetes & Metabolism·Joshua D SmithTobias Else

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