PMID: 9164060Apr 1, 1997Paper

Secretion of different types of gelatinases from cultured human keratinocytes

The Journal of Dermatology
T KobayashiT Nishikawa

Abstract

We investigated gelatinolytic enzymes derived from cultured human keratinocytes. Using a zymograph, we detected 92 kDa and 72 kDa gelatinases as major components and 83 kDa as a minor component from a conditioned cultured medium (BSL-K110, Kyokutoseiyaku Co.) of keratinocytes. After several passages, the 72 kDa band disappeared, and the 83 kDa band became dominant in another conditioned culture medium (K-GM, Kurashikibouseki Co.); these keratinocytes had a relatively differentiated appearance. These results suggest that some mechanism may regulate the secretion of selected types of gelatinase from keratinocytes under different conditions.

References

Apr 1, 1990·Trends in Genetics : TIG·L M Matrisian
Jan 1, 1994·Archives of Dermatological Research·C MauchE A Bauer
Feb 1, 1993·The Journal of Investigative Dermatology·T V KarelinaA Z Eisen
Jan 1, 1996·Dermatology : International Journal for Clinical and Investigative Dermatology·T KobayashiT Nishikawa

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Citations

Jun 16, 2001·The Journal of Investigative Dermatology·G J ThomasJ F Marshall
Jul 24, 1998·The Journal of Dermatology·T Kobayashi, K Sakuraoka
Nov 25, 2004·Experimental Dermatology·Ching-Shuang WuHsin-Su Yu
Nov 8, 2007·Photodermatology, Photoimmunology & Photomedicine·Renato Marchiori BakosNathália Costaguta Matas Soles Masiero
Jun 8, 2000·Matrix Biology : Journal of the International Society for Matrix Biology·A BertonG Bellon

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