Secretive bacterial pathogens and the secretory pathway

Traffic
Hubert Hilbi, Albert Haas

Abstract

Eukaryotic cells possess two extensive endomembrane systems, each consisting of several sub-compartments connected by vesicular trafficking. One of these systems, the endocytic pathway, serves incoming traffic, and the other system, the secretory pathway (SP), is responsible for surface-bound traffic of intracellularly formed vesicles. Compartments derived of either system can be colonized by intracellular pathogens. In this review, we discuss the interactions between the SP and prominent intracellular bacterial pathogens of the genera Legionella, Brucella, Chlamydia and Salmonella. We emphasize secreted bacterial effector proteins, which directly manipulate host components of this pathway.

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Citations

Sep 24, 2013·PloS One·Christopher F HarrisonHubert Hilbi
May 16, 2014·Applied Biochemistry and Biotechnology·Zebing ZhuJie Zhang
Jan 15, 2016·Cellular Microbiology·José Carlos Santos, Jost Enninga
Aug 21, 2012·Traffic·Mary-Pat SteinAngela Wandinger-Ness
Jul 10, 2015·ACS Infectious Diseases·Christopher F HarrisonHubert Hilbi
Jul 23, 2013·Molecular Microbiology·Jeffrey M ChenStewart T Cole
Oct 31, 2013·Cellular Microbiology·Christine HoffmannHubert Hilbi
Apr 20, 2016·Frontiers in Cellular and Infection Microbiology·Nora Mellouk, Jost Enninga
Oct 7, 2015·Frontiers in Immunology·Sylvia Simon, Hubert Hilbi
Apr 16, 2015·Microbiology·Christopher F HarrisonHubert Hilbi
Mar 11, 2015·Traffic·J Bernd HelmsJos F Brouwers
Jun 18, 2015·Frontiers in Cellular and Infection Microbiology·Jo-Ana HerwegHubert Hilbi
Apr 26, 2015·Seminars in Immunology·Gernot Sellge, Thomas A Kufer
Mar 1, 2016·Trends in Microbiology·Nicolas PersonnicHubert Hilbi
Sep 25, 2014·Frontiers in Cellular and Infection Microbiology·Christian Manske, Hubert Hilbi
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Dec 12, 2017·Frontiers in Cellular and Infection Microbiology·Kevin BärlocherHubert Hilbi
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May 28, 2019·Virulence·Ka Yin LeungBupe A Siame
Oct 24, 2014·The Journal of Biological Chemistry·Stephen WeberHubert Hilbi
Jul 29, 2020·Cellular Microbiology·Anna Leoni SwartHubert Hilbi

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