PMID: 914652Jul 1, 1977

Secretory behaviour of hypertrophic and hyperplastic salivary gland

The Histochemical Journal
T BARKA, G T Burke


The enzyme content and the secretory behaviour of normal rat salivary glands were compared with these properties in glands made hypertrophic and hyperplastic by the chronic administration of isoproterenol. The enlarged glands displayed reductions in the concentrations of ribonuclease, deoxyribonuclease and amylase. The secretory behaviour in vivo was similar for all enzymes in both types of glands, but the enlarged glands secreted a lower percentage of their content in vitro. The reduction in amylase activity was shown by immunological techniques to be due to a reduction in the number of enzyme molecules. The reduction in ribonuclease activity was not due to changes in the level of ribonuclease inhibitors.


Mar 25, 1974·Biochemical and Biophysical Research Communications·T KanamoriT Nagatsu
Feb 1, 1974·The Australian Journal of Experimental Biology and Medical Science·B Feiglin, P C Reade
May 1, 1972·The Journal of Cell Biology·J D CastleG E Palade
May 23, 1969·Zeitschrift für Zellforschung und mikroskopische Anatomie·J M Radley
Sep 1, 1965·Experimental Cell Research·T BARKA
Mar 1, 1967·Journal of Ultrastructure Research·M Takahama, T BARKA
Oct 9, 1967·Biochimica Et Biophysica Acta·P Byrt, S Glanvill
Aug 1, 1962·The American Journal of Physiology·C A SCHNEYER
Feb 1, 1963·Proceedings of the Society for Experimental Biology and Medicine·C A SCHNEYER, J M SHACKLEFORD
Mar 30, 1963·Annals of the New York Academy of Sciences·H WELLS
Jan 1, 1964·International Series of Monographs on Oral Biology·M SCHRAMM
Feb 3, 1965·Biochemical and Biophysical Research Communications·A BDOLAH, M SCHRAMM
May 1, 1965·Journal of Dental Research·L M SREEBNYM ROBINOVITCH
Mar 1, 1965·Experimental Cell Research·T BARKA

Related Concepts

Precipitin Tests
Enzymes, antithrombotic
Hypertrophic Cardiomyopathy
Ribonuclease Activity
Epithelioid Hemangioma of Skin
Amylase Activity
Alkaline DNase
Hypertrophic Disorder of Skin, Unspecified
Alkaline Ribonuclease

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