Secretory component of immunoglobulin A in maternal serum and the prediction of preterm delivery

American Journal of Obstetrics and Gynecology
J C SchellenbergR L Zhou

Abstract

Our purpose was to determine whether the secretory component of immunoglobulin A in maternal serum predicts delivery before 34 weeks' gestation. Primigravid women of an urban population in New Zealand were recruited at booking into a prospective longitudinal nested case control study (n = 1651; after exclusions and withdrawals, n = 1511). Serum was collected at 8 to 12 weeks, 15 to 18 weeks, 21 to 24 weeks, 28 to 30 weeks, and 36 to 38 weeks of gestation and 6 weeks post partum. Concentrations of the secretory component of immunoglobulin A were determined by enzyme-linked immunosorbent assay in all women who were delivered preterm (n = 53) and in controls randomly selected from women delivered at > or =37 weeks' gestation (n = 178). Serum concentrations of the secretory component of immunoglobulin A were similar in women delivered at term or preterm throughout pregnancy (n = 21 delivered at <34 weeks and n = 32 at 34 to 36.9 weeks, incidence 3.5%). Receiver-operator characteristic curves showed no discriminating ability of the secretory component of immunoglobulin A. Smokers had 50% higher concentrations than nonsmokers did (p < 0.0001 by analysis of variance). The secretory component of immunoglobulin A in maternal serum does ...Continue Reading

References

Apr 15, 1991·Biochemical and Biophysical Research Communications·T Wilson, D L Christie
Oct 26, 1988·Journal of Immunological Methods·D Kvale, P Brandtzaeg
Nov 15, 1984·American Journal of Obstetrics and Gynecology·B S BlockR K Creasy
Aug 1, 1995·American Journal of Obstetrics and Gynecology·M J Keirse
Sep 1, 1994·Prostaglandins·T WilsonP W Howie
May 1, 1994·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·S A ObedT E Elkins
Sep 1, 1993·Baillière's Clinical Obstetrics and Gynaecology·J Lumley
Apr 1, 1993·American Journal of Obstetrics and Gynecology·R K Creasy
Dec 1, 1995·Clinical Obstetrics and Gynecology·C J Lockwood

❮ Previous
Next ❯

Citations

Mar 11, 2004·Journal of Perinatal Medicine·Simone GlasowRenaldo Faber
Mar 10, 2001·Journal of Perinatal Medicine·S AbitzschR Faber
Aug 2, 2000·American Journal of Obstetrics and Gynecology·E R Norwitz, T Wilson
Aug 2, 2000·American Journal of Obstetrics and Gynecology·R A NorthJ C Schellenberg
Aug 24, 1999·British Journal of Obstetrics and Gynaecology·R A NorthJ C Schellenberg
May 2, 2001·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·D A Dempsey, N L Benowitz
Jun 30, 2000·Human Reproduction·S MuttukrishnaC W Redman
Mar 12, 2003·Prostaglandins, Leukotrienes, and Essential Fatty Acids·J-C SchellenbergC C Van Ee
Jan 9, 2004·The Journal of Nutritional Biochemistry·Jane C-J ChaoChin-Fa Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.