PMID: 7540300Apr 1, 1995Paper

Secretory symptoms from metastatic adrenal cortical carcinoma responding to octreotide

Postgraduate Medical Journal
H S PandhaJ Waxman

Abstract

The prognosis of patients with metastatic adrenal cortical carcinoma is poor, and their disabling symptoms are usually unresponsive to conventional therapy. A patient with Cushing's syndrome secondary to a secretory adrenal cortical carcinoma was treated with octreotide, endocrine therapy and chemotherapy having failed. Treatment led to a dramatic relief of her symptoms with a fall in corticosteroid secretion. Somatostatin analogue therapy for this tumour should be encouraged in view of the lack of alternative palliative treatment.

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