Secular trends of allergic asthma in Danish adults. The Copenhagen Allergy Study

Respiratory Medicine
A LinnebergT Jørgensen

Abstract

Numerous studies have reported increases in asthma prevalence among children world-wide. Less is known about similar trends in adults. We aimed to investigate whether the prevalence of allergic asthma symptoms had increased in an adult general population. Two cross-sectional surveys using identical methods were carried out in 1989 and 1998. A one-page questionnaire on respiratory symptoms was mailed to random samples of 15-41-year-olds living in Copenhagen. The response rates were 86.6% (3624/4185) and 78.8% (2402/3048) in 1989 and 1998, respectively. The questionnaire was validated with specific immunoglobilin E (IgE) positivity as the reference in a random sample of responders in connection with both surveys. We found a significantly increased prevalence of subjects who reported shortness of breath on exposure to pollens (6.6% 0 s. 10.3%, odds ratio 1.61, 95% CI 1.34-1.95), furry animals (5.4% vs. 7.6%, odds ratio 1.45, 95% CI 1.17-1.79), and house dust (7.8% vs. 10.2%, odds ratio 1.35, 95% CI 1.12-1.61). The validation of these symptoms showed that the positive predictive values were reasonably stable over time, which may support that a true increase in allergic asthma has occurred. In conclusion, the prevalence of allergic ...Continue Reading

References

Mar 28, 1992·BMJ : British Medical Journal·D P Strachan, H R Anderson
Apr 4, 1992·BMJ : British Medical Journal·J Britton
Jan 1, 1989·Archives of Disease in Childhood·H R Anderson
Sep 4, 1998·Allergy and Asthma Proceedings·W A GreisnerG A Settipane
Feb 13, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E von Mutius
Mar 27, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·G S Rachelefsky
Jul 28, 1999·Allergy·D P Strachan
Sep 14, 1999·The Journal of Allergy and Clinical Immunology·F E Simons

❮ Previous
Next ❯

Citations

Apr 30, 2002·Thorax·P BagerM Melbye
Jul 17, 2010·Trends in Parasitology·Ida M FribergJoseph A Jackson
Jul 16, 2003·Allergy·J BousquetP Demoly
Nov 18, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P BagerT Westergaard
Jun 16, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A TobíasJ R Banegas
Jul 27, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A LinnebergT Jørgensen
Oct 12, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A LinnebergJ Elberling
Jun 28, 2011·Allergy·A Linneberg
Sep 17, 2004·Clinical Biochemistry·Anita Birgit PetersenNiels Johansen
Feb 13, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H Vally, P J Thompson
Dec 3, 2014·The Journal of Allergy and Clinical Immunology·Moisés A CalderónPascal Demoly
Jan 20, 2015·Gastroenterology·Dale LeeGary D Wu
Dec 20, 2011·Therapeutic Advances in Respiratory Disease·Tunis Ozdoganoglu, Murat Songu
Jun 14, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Helena BackmanEva Rönmark
Jun 23, 2018·Clinical and Molecular Allergy : CMA·Christer JansonMary Kämpe
Jun 22, 2017·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Motoko TakaokaDan Norbäck

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

© 2021 Meta ULC. All rights reserved