Sedation assessment in critically ill patients with bispectral index

European Journal of Anaesthesiology
M L RiessH G Bone

Abstract

Clinical sedation assessment becomes insufficient in deeply sedated patients. Bispectral index as a processed electroencephalogram parameter provides a continuous and observer-independent value reported to change with sedation. The aim of this prospective observational study was to determine the reliability and possible confounding factors of the bispectral index to assess sedation in surgical intensive care patients. Following major surgery, bispectral index, body temperature and electromyographic activity of 44 ventilated patients were recorded. Sedation levels were assessed with Ramsay sedation score. Although bispectral index correlated with Ramsay sedation score (-0.64; P < 0.01) we found that in deeply sedated patients temperature instability and electromyographic activity increased bispectral index. Bispectral index correlated significantly with electromyographic activity (0.80; P < 0.01) and with an increase of body temperature (0.55; P < 0.01) not only in all patients but also in clinically deeply sedated patients (0.57; P < 0.01 and 0.46; P < 0.05). Only under certain conditions, such as low muscular activity and body temperature stability, may the bispectral index be a useful addition to clinical scoring in the sedat...Continue Reading

References

Apr 1, 1992·Drugs·A M BurnsG R Park
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Jun 22, 1974·British Medical Journal·M A RamsayR Goodwin
Oct 20, 1998·Anesthesiology·I J Rampil
Jan 14, 1999·Intensive Care Medicine·C De DeyneF Colardyn
May 26, 1999·Intensive Care Medicine·A M Schulte-TamburenK Peter
Apr 26, 2000·Anesthesiology·J BruhnS L Shafer
Nov 30, 2000·British Journal of Anaesthesia·G MychaskiwJ H Eichhorn

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Citations

Jun 15, 2010·Journal of Pharmacokinetics and Pharmacodynamics·Agnieszka BienertMiłosz Regulski
Nov 26, 2003·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Karin A SamuelsonBengt Fridlund
Sep 17, 2003·Critical Care : the Official Journal of the Critical Care Forum·Dilek MemişZafer Pamukçu
Jul 7, 2009·Heart & Lung : the Journal of Critical Care·Richard ArbourLinda Bucher
Nov 21, 2008·Journal of Clinical Anesthesia·Kazunori YamashitaKoji Sumikawa
Feb 24, 2010·Anaesthesia·A Lamas, Jesús López-Herce
Sep 22, 2009·Applied Biochemistry and Biotechnology·Kavindra Kumar Kesari, Jitendra Behari
Oct 24, 2018·Journal of Magnetic Resonance Imaging : JMRI·Doyeon KimYoung Hee Shin
Sep 30, 2005·Anesthesia and Analgesia·Jean-Paul RoustanXavier Capdevila
Jul 15, 2003·American Journal of Veterinary Research·María F Martín-CanchoJesús Usón-Gargallo
May 19, 2005·Pharmacotherapy·Gilles L Fraser, Richard R Riker
Nov 4, 2011·Electromagnetic Biology and Medicine·LiHua ZengGuoZhen Guo
Oct 1, 2013·Systems Biology in Reproductive Medicine·Joanna JurewiczWojciech Hanke
Oct 6, 2006·Current Opinion in Anaesthesiology·Peter H TonnerJens Scholz
Mar 27, 2003·Current Opinion in Critical Care·Giuseppe Citerio, Manuela Cormio
Mar 27, 2003·Current Opinion in Critical Care·Harvey L EdmondsChristopher B Shields
Feb 10, 2004·AACN Clinical Issues·DaiWai M OlsonJoel C Morgenlander
Jan 20, 2009·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martin SavardBryan Young
Feb 24, 2006·The Annals of Pharmacotherapy·Jaclyn M LeBlancSandra L Kane-Gill
Jan 30, 2008·Anesthesia and Analgesia·Adelaida LamasVicente Martínez
May 7, 2009·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Adelaida LamasVicente Martínez
Nov 6, 2007·AACN Advanced Critical Care·Daiwai M OlsonDavid B Auyong
Jan 21, 2017·Experimental and Therapeutic Medicine·Hui YueJincheng Li
Apr 11, 2008·The Journal of Trauma·Ronald PauldineDavid W Kaczka
Aug 13, 2011·Veterinary Anaesthesia and Analgesia·Flavia RestituttiOuti M Vainio
Apr 25, 2021·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Shoko Yamada, Yuko Ikematsu

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