Sedentary Behavior, Exercise, and Cardiovascular Health

Circulation Research
Carl J LavieSteven N Blair

Abstract

Sedentary behavior and physical inactivity are among the leading modifiable risk factors worldwide for cardiovascular disease and all-cause mortality. The promotion of physical activity and exercise training (ET) leading to improved levels of cardiorespiratory fitness is needed in all age groups, race, and ethnicities and both sexes to prevent many chronic diseases, especially cardiovascular disease. In this state-of-the-art review, we discuss the negative impact of sedentary behavior and physical inactivity, as well as the beneficial effects of physical activity /ET and cardiorespiratory fitness for the prevention of chronic noncommunicable diseases, including cardiovascular disease. We review the prognostic utility of cardiorespiratory fitness compared with obesity and the metabolic syndrome, as well as the increase of physical activity /ET for patients with heart failure as a therapeutic strategy, and ET dosing. Greater efforts at preventing sedentary behavior and physical inactivity while promoting physical activity, ET, and cardiorespiratory fitness are needed throughout the healthcare system worldwide and particularly in the United States in which the burden of cardiometabolic diseases remains extremely high.

References

Sep 1, 1977·The Journal of Physiology·P Andersen, J Henriksson
Sep 1, 1978·American Journal of Epidemiology·R S PaffenbargerR T Hyde
Mar 1, 1966·American Journal of Epidemiology·R S PaffenbargerM C Thorne
Nov 1, 1994·The Journal of Clinical Investigation·R P XiaoE G Lakatta
Jan 1, 1994·Journal of Molecular and Cellular Cardiology·P M ButtrickJ Scheuer
Dec 13, 1996·Biochemical and Biophysical Research Communications·A BarrientosF Cardellach
Sep 16, 1998·Lancet·G ErikssenJ Erikssen
Apr 8, 1999·Journal of the American College of Cardiology·P ClarksonJ E Deanfield
Apr 3, 2002·Annals of Internal Medicine·Seamus P WheltonJiang He
Jun 1, 2002·Archives of Internal Medicine·Jerome L Abramson, Viola Vaccarino
Jun 22, 2002·Clinical Physiology and Functional Imaging·Jun SugawaraHirofumi Tanaka
Jan 22, 2003·Scandinavian Journal of Medicine & Science in Sports·Jesper L Andersen
Sep 19, 2003·European Journal of Applied Physiology·Renza Perini, Arsenio Veicsteinas
Nov 6, 2003·Medicine and Science in Sports and Exercise·I-Min Lee
Dec 4, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Michiel W P BleekerMaria T E Hopman
Dec 18, 2004·Exercise and Sport Sciences Reviews·Marc T HamiltonTheodore W Zderic
Jul 23, 2005·Journal of Applied Physiology·John O Holloszy
Sep 16, 2006·Menopause : the Journal of the North American Menopause Society·Kerrie L MoreauDouglas R Seals
Sep 27, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Ulrik WisløffLars J Vatten
Mar 14, 2007·Best Practice & Research. Clinical Rheumatology·J W J Bijlsma, K Knahr
May 24, 2007·PloS One·Simon MelovAlan Hubbard
Jul 20, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K OhkawaraI Tabata
Oct 3, 2007·Medicine and Science in Sports and Exercise·Laura K StewartErin Talbert
Jun 28, 2008·Journal of Applied Physiology·Douglas R SealsHirofumi Tanaka
Aug 22, 2008·Diabetes·Ian R LanzaK Sreekumaran Nair
Aug 30, 2008·Journal of Sport & Exercise Psychology·Bradley M WipfliDaniel M Landers
Apr 7, 2009·Medicine and Science in Sports and Exercise·Peter T KatzmarzykClaude Bouchard
Apr 9, 2009·JAMA : the Journal of the American Medical Association·Christopher M O'ConnorUNKNOWN HF-ACTION Investigators

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Citations

Sep 3, 2019·European Journal of Preventive Cardiology·Carl J LavieCemal Ozemek
Nov 13, 2019·European Journal of Preventive Cardiology·Francesco ZaccardiThomas Yates
Nov 21, 2019·Journal of Women's Health·Carl J LavieCemal Ozemek
Aug 8, 2019·Current Sports Medicine Reports·Carl J LavieAndrew Elagizi
Apr 24, 2020·Circulation Research·Maximilian J SchlossMatthias Nahrendorf
May 13, 2020·Journal of Neurochemistry·Guilherme B de FreitasFernanda G De Felice
Jun 5, 2020·Research Quarterly for Exercise and Sport·Catiane SouzaJefferson Fagundes Loss
Jun 10, 2020·Journal of Physical Activity & Health·Geoffrey M Hudson, Kyle Sprow
Jun 12, 2020·International Journal of Environmental Research and Public Health·Lidewij R RenaudAllard J van der Beek
Jun 3, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Katrine RolidKari Nytrøen
Jul 10, 2020·The Journal of Clinical Hypertension·Kazuomi KarioUNKNOWN Hypertension Cardiovascular Outcome Prevention, Evidence in Asia (HOPE Asia) Network
Jun 17, 2020·Diabetes/metabolism Research and Reviews·Setor K KunutsorJari A Laukkanen
Jul 29, 2020·Scottish Medical Journal·Baskaran Chandrasekaran, Thiru Balaji Ganesan
Aug 15, 2020·The Journal of School Health·Rena C MoonJulie Gazmararian
Sep 2, 2020·Current Obesity Reports·Andrew ElagiziSteven N Blair
Sep 24, 2020·Revista da Associação Médica Brasileira·Cristiano Silva PinhoFrancisco José Gondim Pitanga
Apr 27, 2019·Postgraduate Medicine·Salvatore Carbone, Carl J Lavie
May 19, 2020·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Aliyu LawanAdamu Ahmad Rufa'i
Sep 4, 2020·International Journal of Environmental Research and Public Health·María Del Rocio Medrano-UreñaJuan de Dios Benítez-Sillero
Aug 23, 2020·The Nurse Practitioner·Geoffrey M HudsonSharon Fruh
Aug 8, 2020·High Altitude Medicine & Biology·Reinhard PuehringerMartin Burtscher
Mar 3, 2020·Frontiers in Physiology·Charles S ChungPatrick J Mueller
Apr 16, 2020·International Journal of Environmental Research and Public Health·Yaira Barranco-Ruiz, Emilio Villa-González
Sep 29, 2019·European Heart Journal·Carl J LavieSergey Kachur
Feb 6, 2020·European Journal of Preventive Cardiology·Sae Young JaeJari A Laukkanen
Jul 4, 2020·Heart·Verónica Cabanas-SánchezDavid Martínez-Gómez
Jun 5, 2020·International Journal of Environmental Research and Public Health·Fabian Schwendinger, Elena Pocecco
Feb 9, 2020·Cardiovascular Drugs and Therapy·Giuseppe Lippi, Fabian Sanchis-Gomar

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