Sedentary behaviour patterns and carotid intima-media thickness in Spanish healthy adult population

Atherosclerosis
Antonio García-HermosoEVIDENT Group

Abstract

The aim of this study was to analyze the association between sedentary behaviour, as assessed by an accelerometer, and mean carotid intima-media thickness (IMT). The study included 263 healthy subjects belonging to the EVIDENT study (59.3% women). Carotid IMT was measured by carotid ultrasonography. Sedentary behaviour was measured objectively over 7 days using ActiGraph accelerometers. Thresholds of 10 consecutive minutes were used to establish sedentary bouts, and assess the number (n/day), and length ≥10 min (min/day). Total sedentary time and sedentary time in bouts ≥10 min was higher in participants with a larger mean carotid IMT (>P75). Otherwise, this sedentary time in bouts ≥10 min parameter was weakly associated with augmented carotid IMT injury in the logistic regression model. Total sedentary time and sedentary time in bouts ≥10 min, as assessed by accelerometer, was positively but weakly associated with carotid IMT. Equally, this sedentary time in bouts ≥10 min was associated with carotid injury, but disappears after adjusting for potential confounders. These findings support that reducing sedentary time and increasing breaks in bouts of sedentary time might represent a useful additional strategy in the cardiovascul...Continue Reading

Associated Clinical Trials

References

Mar 7, 2002·The American Journal of Cardiology·J David Spence
Mar 7, 2002·The American Journal of Cardiology·Jacques D Barth
Mar 19, 2005·Journal of Hypertension·Eoin O'BrienUNKNOWN European Society of Hypertension Working Group on Blood Pressure Monitoring
Nov 19, 2005·Medicine and Science in Sports and Exercise·Kong Y Chen, David R Bassett
Nov 9, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·N P E KadoglouC D Liapis
Feb 7, 2008·Diabetes Care·Genevieve N HealyNeville Owen
Dec 10, 2009·Medicine and Science in Sports and Exercise·Tatiana Y WarrenSteven N Blair
Jun 29, 2010·Medicine and Science in Sports and Exercise·Leena ChoiMaciej S Buchowski
Jan 29, 2011·Diabetes Care·Andrea BankoskiAnnemarie Koster
Jul 22, 2011·The New England Journal of Medicine·Joseph F PolakRalph B D'Agostino
May 1, 2012·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·UNKNOWN Sedentary Behaviour Research Network
Oct 5, 2012·Medicine and Science in Sports and Exercise·Tineke ScheersJohan Lefevre
Mar 12, 2013·Internal and Emergency Medicine·Fabio GalettaGino Santoro
Jul 19, 2013·Medicine and Science in Sports and Exercise·Charles E MatthewsJay H Fowke
Apr 20, 2014·Atherosclerosis·Manuel A Gomez-MarcosUNKNOWN EVIDENT Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.