Sedentary Patterns, Physical Activity, and Cardiorespiratory Fitness in Association to Glycemic Control in Type 2 Diabetes Patients

Frontiers in Physiology
Luís B SardinhaPedro B Júdice

Abstract

Background: Sedentary behavior has been considered an independent risk factor for type-2 diabetes (T2D), with a negative impact on several physiological outcomes, whereas breaks in sedentary time (BST) have been proposed as a viable solution to mitigate some of these effects. However, little is known about the independent associations of sedentary pursuits, physical activity, and cardiorespiratory fitness (CRF) variables with glycemic control. We investigated the independent associations of total sedentary time, BST, moderate-to-vigorous physical activity (MVPA), and CRF with glycemic outcomes in patients with T2D. Methods: Total sedentary time, BST, and MVPA were assessed in 66 participants (29 women) with T2D, using accelerometry. Glucose and insulin were measured during a mixed meal tolerance test, with the respective calculations of HOMA-IR and Matsuda index. Glycated hemoglobin (HbA1c) was also analyzed. CRF was measured in a maximal treadmill test with breath-by-breath gases analysis. Multiple regressions were used for data analysis. Results: Regardless of CRF, total sedentary time was positively associated with HbA1c (β = 0.25, p = 0.044). Adjusting for MVPA, total sedentary time was related to fasting glucose (β = 0.32,...Continue Reading

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Citations

Sep 29, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·A C PaingS F M Chastin
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Apr 2, 2021·European Journal of Public Health·Pedro B JúdiceLuís B Sardinha
Jul 21, 2021·Clinical Science·Amarens van der VaartMartin H de Borst

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Methods Mentioned

BETA
X-ray

Software Mentioned

SPSS
QDR
Actilife
Cosmed

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