Seeing is believing: video classification for computed tomographic colonography using multiple-instance learning.

IEEE Transactions on Medical Imaging
Shijun WangRonald M Summers

Abstract

In this paper, we present development and testing results for a novel colonic polyp classification method for use as part of a computed tomographic colonography (CTC) computer-aided detection (CAD) system. Inspired by the interpretative methodology of radiologists using 3-D fly-through mode in CTC reading, we have developed an algorithm which utilizes sequences of images (referred to here as videos) for classification of CAD marks. For each CAD mark, we created a video composed of a series of intraluminal, volume-rendered images visualizing the detection from multiple viewpoints. We then framed the video classification question as a multiple-instance learning (MIL) problem. Since a positive (negative) bag may contain negative (positive) instances, which in our case depends on the viewing angles and camera distance to the target, we developed a novel MIL paradigm to accommodate this class of problems. We solved the new MIL problem by maximizing a L2-norm soft margin using semidefinite programming, which can optimize relevant parameters automatically. We tested our method by analyzing a CTC data set obtained from 50 patients from three medical centers. Our proposed method showed significantly better performance compared with seve...Continue Reading

References

Jan 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·H H Bülthoff, S Edelman
Apr 9, 1999·Nature Neuroscience·M J TarrI Gauthier
Jan 29, 2002·IEEE Transactions on Medical Imaging·H Yoshida, J Näppi
Jan 1, 2003·Computer Methods and Programs in Biomedicine·D E MaroulisD A Karras
Oct 2, 2003·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Stavros A KarkanisM Tzivras
Dec 6, 2003·The New England Journal of Medicine·Perry J PickhardtWilliam R Schindler
Nov 24, 2004·IEEE Transactions on Medical Imaging·Jianhua YaoRonald M Summers
Jul 1, 2005·Radiology·Michael E ZalisUNKNOWN Working Group on Virtual Colonoscopy
Aug 27, 2005·IEEE Transactions on Pattern Analysis and Machine Intelligence·Hanchuan PengChris Ding
Dec 21, 2007·IEEE Transactions on Medical Imaging·Ender KonukogluSandy Napel
Mar 13, 2008·IEEE Transactions on Bio-medical Engineering·Tarik A ChowdhuryOvidiu Ghita
Jun 24, 2009·Medical Physics·Janne Näppi, Hiroyuki Yoshida
Jul 28, 2009·Abdominal Imaging·Antonella LostumboAbraham H Dachman
Sep 8, 2009·Academic Radiology·Antonella LostumboAbraham H Dachman
Mar 17, 2010·Academic Radiology·Perry J PickhardtJessica B Robbins
Jul 9, 2010·CA: a Cancer Journal for Clinicians·Ahmedin JemalElizabeth Ward
Oct 19, 2010·International Journal of Computational Intelligence and Applications·Shijun WangRonald M Summers

❮ Previous
Next ❯

Citations

Sep 6, 2014·Medical Image Analysis·Jianfei LiuRonald M Summers
Aug 28, 2014·IEEE Transactions on Medical Imaging·Jaime MelendezClara I Sanchez
Dec 15, 2015·IEEE Transactions on Medical Imaging·Jaime MelendezClara Sanchez
Nov 13, 2019·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Constantinos Loukas, Nicholas P Sgouros
Jan 10, 2021·Computers in Biology and Medicine·Karen Andrea Lara HernandezChristian Baumgartner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Physics in Medicine and Biology
Hongbin ZhuZhengrong Liang
IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society
Shijun WangRonald M Summers
© 2021 Meta ULC. All rights reserved