Seeing it through: translational validation of new medical imaging modalities.

Biomedical Optics Express
Melissa B AldrichTom Wang

Abstract

Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to "bridge the gap" between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.

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Citations

May 10, 2013·Science Translational Medicine·Matthew B SturmThomas D Wang
May 21, 2013·Gastroenterology·Matthew B SturmThomas D Wang
Jan 11, 2013·Biomedical Optics Express·Eva M Sevick-MuracaAli Azhdarinia
Nov 29, 2016·Journal of Biomedical Optics·Paul Kumar Upputuri, Manojit Pramanik
Oct 22, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rachelle CrescenziManus J Donahue
Jan 12, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Matthijs D LinssenWouter B Nagengast

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Methods Mentioned

BETA
fluorescence imaging
biopsy
imaging techniques
fluorescence imaging technique
xenografts
fluorescent imaging techniques

Software Mentioned

SciPort
PAT

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