Segmental resection spares pulmonary function in patients with stage I lung cancer

The Annals of Thoracic Surgery
Robert J KeenanTibetha Santucci

Abstract

Segmental resection for stage I non-small cell lung cancer remains controversial. Reports suggest that segmentectomy confers no advantage in preserving lung function and compromises survival. This study was undertaken to assess the validity of those assertions. We retrospectively analyzed patients undergoing lobectomy (n = 147) or segmentectomy (n = 54) for stage I non-small cell lung cancer between March 1996 and June 2001. All patients were included in the survival analysis. Pulmonary function testing was obtained preoperatively and at 1 year and included forced vital capacity, forced expiratory volume in 1 second, maximum voluntary ventilation, diffusing capacity, and stair-stepper exercise. Patients with recurrent disease (lobectomy, n = 32; segmentectomy, n = 10) were excluded in the pulmonary function testing analysis to avoid the confounding variables of tumor or treatments. Preoperative pulmonary function tests in segmentectomy patients were significantly reduced compared with lobectomy (forced expiratory volume in 1 second, 75.1% versus 55.3%; p < 0.001). At 1 year, lobectomy patients experienced significant declines in forced vital capacity (85.5% to 81.1%), forced expiratory volume in 1 second (75.1% to 66.7%), maxim...Continue Reading

References

Mar 1, 1990·The Annals of Thoracic Surgery·R C ReadR C Schaeffer
Nov 1, 1990·The Annals of Thoracic Surgery·T IshidaK Sugimachi
Nov 1, 1985·The Journal of Thoracic and Cardiovascular Surgery·L E ErrettD D Munro
Apr 1, 1997·The Journal of Thoracic and Cardiovascular Surgery·R J LandreneauK S Naunheim
Sep 26, 1997·The Journal of Thoracic and Cardiovascular Surgery·K KodamaH Yokouchi
Jun 10, 1998·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·T SakamotoM Yoshimura
Aug 12, 1998·The Journal of Thoracic and Cardiovascular Surgery·T TakizawaK Honma
Oct 13, 1998·The Annals of Thoracic Surgery·R J KorstD Stover
Sep 2, 1999·The Journal of Thoracic and Cardiovascular Surgery·T TakizawaY Kurita
Oct 28, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·H Shennib
May 9, 2002·The Annals of Thoracic Surgery·Koichi YoshikawaTakashi Mori
May 23, 2002·The Annals of Thoracic Surgery·Daniel L MillerPeter C Pairolero

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Citations

Sep 16, 2006·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Satoshi YamamotoSumitaka Arima
Apr 11, 2008·General Thoracic and Cardiovascular Surgery·Morihito Okada
Nov 26, 2013·General Thoracic and Cardiovascular Surgery·Kazuhiro UedaKimikazu Hamano
Jul 11, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Shingo IwanoShinji Naganawa
Jan 8, 2004·Seminars in Thoracic and Cardiovascular Surgery·Amit N PatelRodney J Landreneau
Mar 1, 2012·Interactive Cardiovascular and Thoracic Surgery·Maya K De ZoysaMarco Scarci
Feb 22, 2013·Interactive Cardiovascular and Thoracic Surgery·Hirohisa KatoMitsuaki Sadahiro
Oct 1, 2011·Journal of the National Cancer Institute·Sarah E BillmeierSelwyn O Rogers
Aug 9, 2013·Journal of the National Cancer Institute·Jun-ichi NitadoriPrasad S Adusumilli
May 11, 2011·American Journal of Clinical Oncology·Bhupesh ParasharK S Clifford Chao
Jan 26, 2011·The Cancer Journal·Chaitan K NarsuleHiran C Fernando
May 17, 2007·Annals of Surgical Oncology·Amgad El-SherifRodney J Landreneau
Dec 18, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Shintaro TarumiHiroyasu Yokomise
Apr 8, 2014·Journal of Vascular and Interventional Radiology : JVIR·Carole A RidgeStephen B Solomon
Dec 11, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Feichao BaoJian Hu
Apr 10, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Christopher CaoTristan D Yan
Sep 4, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Brandon StoneInga S Grills
Sep 10, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Onkar V KhullarFelix G Fernandez
Feb 6, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Cardinale B SmithJuan P Wisnivesky
Nov 5, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Marcello Carlo AmbrogiAlfredo Mussi
Jan 20, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Matthias GuckenbergerInga S Grills
Feb 6, 2016·The Annals of Thoracic Surgery·Robert J CerfolioBenjamin Wei
Jul 22, 2009·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Kosuke KashiwabaraHirotsugu Kohrogi
Jan 11, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Emanuela TaioliRaja M Flores
Apr 1, 2014·The Annals of Thoracic Surgery·Yasuhiro TsutaniMorihito Okada
Nov 28, 2013·The Journal of Thoracic and Cardiovascular Surgery·Nasser K AltorkiUNKNOWN I-ELCAP Investigators
Dec 5, 2012·Chest·Jessica DoningtonUNKNOWN Thoracic Oncology Network of the American College of Chest Physicians and the Workforce on Evidence-Based Surgery of the Soc
Mar 3, 2011·Chest·James E Lynch, Joseph B Zwischenberger
Aug 13, 2013·Thoracic Surgery Clinics·Morihito Okada
Apr 10, 2012·The Annals of Thoracic Surgery·Matthew J SchuchertRodney J Landreneau
May 9, 2012·The Annals of Thoracic Surgery·Aritoshi HattoriShiaki Oh

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