PMID: 9531407Apr 8, 1998Paper

Segmental spinal dysgenesis: a report of three cases

Journal of Pediatric Orthopedics
L O HughesC M Glasier

Abstract

Segmental spinal dysgenesis is an uncommon congenital spinal defect characterized by localized segmental agenesis of the upper lumbar or thoracolumbar spine. Bony defects include significant focal canal stenosis, hypoplastic or absent vertebrae, subluxation of the spinal column, and instability. The distal bony architecture is usually normal but may be bifid. There is significant narrowing of the thecal sac and absence of adjacent nerve roots at the level of the lesion. Distal neurologic deficits are variable in severity, the prevalence of neurogenic bladder is high, and associated anomalies are common. Progressive kyphosis is inevitable. The cause is unknown, but an association with maternal diabetes and with various medications and toxins has been noted. Other authors suggested a relation to an aberrant segmental vascular supply. Treatment should be directed at the establishment and maintenance of spinal stability and arrest of the progressive kyphosis. It should consist of early anterior and posterior arthrodesis, with or without anterior decompression of the cord. Accurate visualization of this unusual deformity is difficult with conventional radiographic techniques. Three-dimensional computerized tomographic reconstruction...Continue Reading

References

Apr 1, 1988·Neurosurgery·R M ScottL Karlin
Sep 1, 1970·Archives of Neurology·D L PriceE P Richardson
Jul 1, 1982·Spine·S P Montgomery, J E Hall
Aug 1, 1980·Neurosurgery·D Pang, H J Hoffman
Jul 1, 1980·Spine·D W McKay, S S Nason

❮ Previous
Next ❯

Citations

Jun 4, 2005·Pediatric Radiology·Elodie ZanaGuy Sebag
Oct 6, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ruth E BristolHarold L Rekate
Feb 3, 2009·Pathology, Research and Practice·Gyula Richárd NagyJános Rigó
Mar 13, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Melissa Valdez QuintanaElka Miller
Sep 11, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S M MorellE Ocal
Jun 3, 2008·The Neuroradiology Journal·M EmmanouilidouI Tsitouridis
Aug 21, 2001·Journal of Child Neurology·A WeberM Obladen
Dec 12, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Kyu-Chang WangJi Yeoun Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Related Papers

Prenatal Diagnosis
N FratelliA T Papageorghiou
Gynecologic and Obstetric Investigation
Cem DaneBanu Dane
© 2022 Meta ULC. All rights reserved