Segmental ulcerative vasculitis: a cutaneous manifestation of Takayasu's arteritis.

International Wound Journal
Assen L DourmishevRobert A Schwartz

Abstract

A 16-year-old girl with pyoderma gangrenosum (PG)-like skin lesions on the extremities, trunk and face developed Takayasu's arteritis (TA; pulseless disease). After 3 years under maintenance cyclosporin A therapy, the patient developed an ischaemic cerebral accident. Severe obstruction of both subclavian and left carotid arteries was found by Doppler sonography, angiography and computerised axial tomography. Evolution of this disease showed some characteristic findings: (a) PG-like lesions as the first cutaneous manifestation of pulseless disease; (b) methotrexate and cyclosporin A giving good results for the cutaneous lesions, but apparently not exerting an influence on the evolution of TA and the fatal outcome. This morphologic pattern may reflect underlying TA or Wegener's arteritis, and should be termed segmental ulcerative vasculitis.

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Citations

Jun 22, 2010·Rheumatology·Juergen BrunnerSusanne M Benseler
Feb 18, 2016·International Journal of Inflammation·Lyubomir A DourmishevLjubka G Miteva
Jul 14, 2010·International Journal of Dermatology·Aaron Joseph Morgan, Robert A Schwartz
Oct 20, 2018·Frontiers in Pediatrics·Ricardo A G Russo, María M Katsicas
Nov 11, 2018·Rheumatology International·Tsvetoslav Georgiev, Rumen Stoilov

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