Segmentation, Separation and Pose Estimation of Prostate Brachytherapy Seeds in CT Images

IEEE Transactions on Bio-medical Engineering
Huu-Giao NguyenJocelyne Troccaz

Abstract

In this paper, we address the development of an automatic approach for the computation of pose information (position + orientation) of prostate brachytherapy loose seeds from 3-D CT images. From an initial detection of a set of seed candidates in CT images using a threshold and connected component method, the orientation of each individual seed is estimated by using the principal components analysis method. The main originality of this approach is the ability to classify the detected objects based on a priori intensity and volume information and to separate groups of closely spaced seeds using three competing clustering methods: the standard and a modified k-means method and a Gaussian mixture model with an expectation-maximization algorithm. Experiments were carried out on a series of CT images of two phantoms and patients. The fourteen patients correspond to a total of 1063 implanted seeds. Detections are compared to manual segmentation and to related work in terms of detection performance and calculation time. This automatic method has proved to be accurate and fast including the ability to separate groups of seeds in a reliable way and to determine the orientation of each seed. Such a method is mandatory to be able to compu...Continue Reading

References

Jul 23, 1999·IEEE Transactions on Medical Imaging·F Zana, J C Klein
Nov 27, 2001·Physics in Medicine and Biology·J F CorbettI W Yeung
Apr 29, 2003·IEEE Transactions on Medical Imaging·Andy TsaiAlan Willsky
Apr 16, 2004·IEEE Transactions on Medical Imaging·V GrauS K Warfield
Sep 28, 2007·IEEE Transactions on Medical Imaging·Vikas SinghMatthew Podgorsak
Jul 17, 2010·Medical Physics·P FallavollitaG Fichtinger
Dec 15, 2010·Proceedings·Nathanael KuoJerry Prince
Jul 21, 2011·Physics in Medicine and Biology·Junghoon LeeJerry L Prince
Aug 2, 2011·Medical Engineering & Physics·Nathanael KuoJunghoon Lee
Mar 27, 2012·International Journal of Computer Assisted Radiology and Surgery·Eric MoultPascal Fallavollita
Jul 13, 2012·Medical Image Analysis·Ehsan DehghanGabor Fichtinger
Feb 8, 2014·International Journal of Computer Assisted Radiology and Surgery·Chiara Amat di San FilippoPascal Fallavollita
Oct 6, 2014·Medical Physics·Charles-Antoine Collins FeketeLuc Beaulieu

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Citations

Jun 24, 2017·International Journal of Computer Assisted Radiology and Surgery·Guobin ZhangHaisong Jiang

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