PMID: 5921385Dec 2, 1966

Segregation of sister chromatids in mammalian cells

Science
K G LarkH C Minocha

Abstract

Segregation of sister chromatids in embryonic mouse cells in primary tissue culture is not random. In mitosis those chromatids replicated on a DNA template synthesized during the preceding division cycle are separated from those constructed on a template synthesized two division cycles previously. Segregation in cells of the Chinese hamster follows a similar, but less pronounced, pattern.

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Related Concepts

Autoradiography
Cell Division Phases
Chromosomes
DNA, Double-Stranded
Fibroblasts
Cricetus
Culture Techniques

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