Seizures and therapy in adolescents with uncomplicated epilepsy

Seizure : the Journal of the British Epilepsy Association
Lena K A RätyBrigitta A Söderfeldt

Abstract

This study aimed to describe seizures and their therapy among Swedish adolescents, aged 13-22, with active but uncomplicated epilepsy. The adolescents answered questionnaires (158/193). Data were also obtained from medical records. Epileptic seizure types could be specified in 92.1% of the cases. Predominant types were Primary Generalised Tonic-Clonic Seizures and Partial Complex Seizures with Secondary Generalisation. Clinical diagnoses by physicians were unspecified in 25.8%. Ninety percent were on antiepileptic drugs (AEDs), most commonly valproate and carbamazepine. New AEDs were used in 9.3% of the cases and polytherapy in 13.9%. More than 40% of the respondents had seizures despite AED treatment. Side effects of AEDs were experienced by 61%, most commonly tiredness, concentration difficulties and headache. Patients on polytherapy experienced significantly more side effects. The choice of a new AED over a traditional one was not related to seizure type or seizure control. Many adolescents had persistent seizures despite treatment at a specialist regional epilepsy centre. This, plus the high reported rate of side effects of AED treatment, suggests that treatment is not optimal for the group studied. As traditional AEDs stro...Continue Reading

References

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Citations

May 5, 2005·Epilepsy & Behavior : E&B·Gus A BakerHelen Soteriou
Oct 2, 2003·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Lena K A RätyBirgitta A Söderfeldt
Jan 14, 2009·Seizure : the Journal of the British Epilepsy Association·Helena GauffinBirgitta Söderfeldt
Jul 28, 2004·Seizure : the Journal of the British Epilepsy Association·Lena K A RätyBodil M Wilde Larsson
Dec 17, 2014·Epilepsy & Behavior : E&B·Ksenija Gebauer-BukurovKsenija Bozic

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