Seizures in setting of dementia

Current Treatment Options in Neurology
Kartik Sivaraaman, Vimala S Vajjala

Abstract

Dementia, especially Alzheimer's disease, is an important cause of seizures and epilepsy midst the elderly. With the increasing life span, the incidence of dementia and epilepsy is expected to increase exponentially. Care of patients with advanced dementia can be demanding and seizures add to this burden. Though recognition of seizures in these patients can be difficult, seizures in these patients tend to be highly responsive to pharmacological therapy. However, choosing the right antiepileptic drug can be a challenge and complicated by altered kinetics and polypharmacy. While ongoing seizures can worsen the cognitive status in these patients, antiepileptic drugs could also add to the cognitive burden. The newer generation drugs show promise in terms of their side effect profile without compromising on the efficacy.

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