PMID: 2510493Nov 1, 1989Paper

Selected ultratrace elements in total parenteral nutrition solutions

The American Journal of Clinical Nutrition
Y N BernerM Shike

Abstract

Ultratrace elements are potentially essential (eg. boron, molybdenum, nickel, and vanadium) or toxic (eg, aluminum and cadmium) in humans. Long-term total parenteral nutrition (TPN) patients can inadvertently receive significant amounts of ultratrace elements present as contaminants in TPN solutions. We determined the intake of selected ultratrace elements from a standard TPN solution and compared it with the amount reported to be absorbed from food in normal subjects. Contamination of TPN solutions with ultratrace elements was widespread and variable. The daily intakes of Mo, Ni, V. and Cd from this contamination were comparable to the amounts reported to be absorbed through the gastrointestinal tract in normal subjects. Al intake was high; B intake was low, approximately 10% of the amount absorbed by normal subjects. Thus, TPN solutions are contaminated with significant amounts of ultratrace elements. The biological significance of the intravenous infusion of these ultratrace elements is unclear and requires further investigation, particularly in home TPN patients.

Citations

Feb 18, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Joseph I BoullataUNKNOWN American Society for Parenteral and Enteral Nutrition
May 25, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·J K FrielW L Andrews
Jul 27, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·M M Pluhator-MurtonL M Gramlich
Apr 7, 2016·European Journal of Clinical Nutrition·P StehleK S Kuhn
Apr 26, 2016·Journal of Pediatric Gastroenterology and Nutrition·Robert A Yokel, Jason M Unrine
Jul 15, 2000·Journal of Pediatric Gastroenterology and Nutrition·E SieversJ Schaub
Aug 24, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·G Hardy, C Reilly
Apr 15, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Catherine J KleinPhylis B Moser-Veillon
Aug 10, 2011·JPEN. Journal of Parenteral and Enteral Nutrition·Imad F BtaicheKathleen B Welch
Feb 11, 2015·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Prinessa Chellan, Peter J Sadler
Jun 1, 1992·Irish Journal of Medical Science·D J Hehir, T F Gorey

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