Selection and electrophoretic characterization of Salmonella enterica subsp. enterica biocide variants resistant to antibiotics

Polish Journal of Veterinary Sciences
B Futoma-KołochG Bugla-Płoskońska

Abstract

The proposed research outlines a serious common concern of Salmonella resistance to antimicrobials following prolonged exposure to the disinfectants (biocides). These phenotypes of bacteria could potentially result in hard to treat infections. Typical for avian sources, biocide sensitive S. enterica subsp. enterica serovars: Typhimurium, Enteritidis, Virchow and Zanzibar and their isogenic biocide-tolerant variants were studied in order to investigate bacteriostatic effect of two commercially available biocide formulations: potassium peroxymonosulfate (P) and dodecylamine based structure (triamine, D). We found that cultivating of the bacteria in the medium supplemented with a blend containing P did not influence their antibiotic susceptibility pattern. In contrast, tolerance of bacteria to D compound resulted in resistance to co-trimoxazole, cefotaxime and ciprofloxacin of which two cefotaxime and ciprofloxacin are used commonly for the treatment of invasive Salmonella infections in humans. The dependency between OMP patterns and the level of Salmonella survival in media containing the biocides was observed merely in serovar Typhimurium. In conclusion, these results suggest that Salmonella strains challenged by prolonged treat...Continue Reading

References

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Jun 9, 2004·Seminars in Pediatric Infectious Diseases·Frederick J AnguloTimothy J Barrett
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Citations

Nov 15, 2016·Foodborne Pathogens and Disease·Maria Luisa Fernández MárquezRosario Lucas López
Nov 1, 2018·Current Medicinal Chemistry·Bożena Futoma-KołochAndrzej Gamian
Jan 12, 2021·World Journal of Microbiology & Biotechnology·Ewa ObłąkAnna Wieczyńska

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