Selection and maintenance of androdioecy in Caenorhabditis elegans.

Genetics
Andrew D Stewart, Patrick C Phillips

Abstract

Caenorhabditis elegans is an androdioecious nematode composed of selfing hermaphrodites and rare males. A model of male maintenance demonstrates that selfing rates in hermaphrodites cannot be too high or else the frequency of males will be driven down to the rate of spontaneous nondisjunction of the X chromosome. After their outcrossing ability is assessed, males are found to skirt the frequency range in which they would be maintained. When male maintenance is directly assessed by elevating male frequency and observing the frequency change through time, males are gradually eliminated from the population. Males, therefore, appear to reproduce at a rate just below that necessary for them to be maintained. Populations polymorphic for a mutation (fog-2) that effectively changes hermaphrodites into females demonstrate that there is strong selection against dioecy. Factors such as variation in male mating ability and inbreeding depression could potentially lead to the long-term maintenance of males.

References

Dec 1, 1979·Developmental Biology·S Ward, J S Carrel
Dec 3, 1992·Nature·W A Van Voorhies
Oct 22, 1991·Proceedings. Biological Sciences·J Hodgkin, T M Barnes
May 1, 1974·Genetics·S Brenner
Nov 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·T E Johnson, W B Wood
Jan 7, 1997·Proceedings of the National Academy of Sciences of the United States of America·C W LaMunyon, S Ward
Mar 24, 1998·Nature·M L BlaxterW K Thomas
May 20, 2000·International Journal of Plant Sciences·C VassiliadisP Vernet
Aug 11, 2000·Evolution; International Journal of Organic Evolution·S C WeeksN Zucker
Jul 20, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·P E Kuwabara, M D Perry
Feb 1, 1993·The American Naturalist·S P OttoM W Feldman
Sep 1, 1976·Evolution; International Journal of Organic Evolution·M D Ross, B S Weir
Apr 1, 1999·Evolution; International Journal of Organic Evolution·Stephen C WeeksBobbi R Crosser
Feb 1, 1997·Evolution; International Journal of Organic Evolution·John Pannell

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Citations

Jun 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Karin KiontkeDavid H A Fitch
Oct 17, 2006·Journal of Evolutionary Biology·F J Janzen, P C Phillips
Aug 23, 2007·Evolution; International Journal of Organic Evolution·Sarah M Eppley, John R Pannell
Jul 18, 2008·Nature·Michael F PalopoliLeonid Kruglyak
Dec 14, 2006·Proceedings. Biological Sciences·Diogo ManoelHenrique Teotónio
Sep 2, 2008·Genetics·Vaishali KatjuUlfar Bergthorsson
Sep 17, 2004·Molecular Biology and Evolution·Asher D Cutter, Samuel Ward
Apr 13, 2006·Proceedings. Biological Sciences·Stephen C WeeksWalter R Hoeh
Apr 18, 2006·Zoology : Analysis of Complex Systems, ZACS·Matthias HerrmannRalf J Sommer
Feb 6, 2007·Trends in Genetics : TIG·Eric S HaagHinrich Schulenburg
Jun 9, 2017·Genetics·Henrique TeotónioCharles F Baer
Jul 12, 2005·Current Biology : CB·Antoine Barrière, Marie-Anne Félix
Jan 27, 2005·Journal of Evolutionary Biology·A D Cutter
Jun 5, 2007·Evolution; International Journal of Organic Evolution·Elie S DolginAsher D Cutter
Jul 7, 2019·G3 : Genes - Genomes - Genetics·Ivo M CheloHenrique Teotónio
May 23, 2015·BMC Evolutionary Biology·Michael F PalopoliPatrick C Phillips
Sep 7, 2019·Genetics·Asher D CutterPatrick C Phillips
Jul 29, 2003·Aging Cell·Diana McCulloch, David Gems
Nov 1, 2016·Evolution; International Journal of Organic Evolution·Samuel P SlowinskiPatrick C Phillips
Apr 22, 2009·BMC Evolutionary Biology·Arielle ClickAndre Pires-daSilva
Feb 13, 2009·Evolution; International Journal of Organic Evolution·Levi T MorranPatrick C Phillips
Nov 8, 2003·Science·Veena PrahladElizabeth B Goodwin
Oct 23, 2009·Nature·Levi T MorranPatrick C Phillips
Feb 17, 2019·G3 : Genes - Genomes - Genetics·Sophie TandonnetAndre Pires-daSilva
Mar 10, 2010·The Journal of Heredity·Jennifer L AndersonPatrick C Phillips
Sep 13, 2011·Current Biology : CB·Jyotiska ChaudhuriAndre Pires-daSilva
Aug 9, 2011·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Martina HöcknerStephen R Stürzenbaum
Apr 7, 2012·Trends in Genetics : TIG·Cristel G ThomasEric S Haag

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