PMID: 7547014Sep 1, 1995Paper

Selection factors for the use of thrombolytic treatment in acute myocardial infarction: a population based study of current practice in the United Kingdom. The European Secondary Prevention Study Group

British Heart Journal
D Ketley, K L Woods

Abstract

To identify and rank the factors that currently limit the use of thrombolytic treatment in patients admitted to hospital with acute myocardial infarction. Weighted sampling study with retrospective data retrieval from clinical records. All hospitals within the Trent region providing acute general medical services. Random sample of 420 patients admitted during February-April 1993 who had acute myocardial infarction as the main discharge diagnosis. Treatment odds ratios (and 95% confidence intervals (CI)) for the use of thrombolysis in patient groups defined by relevant clinical characteristics. The patient population was older and less likely to have ST segment elevation on the initial electrocardiogram than patients entered into the randomised trials of thrombolysis. Thrombolytic treatment was given to 49% of patients (SE 2.4%). After controlling for negative associations with a history of stroke (treatment odds ratio 0.18 (95% CI 0.04 to 0.53)) and peptic ulcer (odds ratio 0.52 (95% CI 0.26 to 1.01)) use of thrombolysis decreased with increasing patient age. This was particularly noticeable for those aged > 74 years (odds ratio 0.17 (95% CI 0.05 to 0.51)) relative to those aged < 65 years. Thrombolysis was less likely to be us...Continue Reading

References

Oct 10, 1992·BMJ : British Medical Journal·A T Elder, K A Fox
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Citations

Jan 29, 2010·Clinical and Experimental Pharmacology & Physiology·Yong-Jian LiUNKNOWN Korea Acute Myocardial Infarction Registry Investigators
Oct 3, 1999·Journal of Accident & Emergency Medicine·J A EdhouseF P Morris
Jun 19, 2012·Journal of the American Medical Directors Association·Henrike J SchoutenJ J M van Delden
Feb 13, 1999·Journal of Electrocardiology·I B MenownA A Adgey
May 17, 2005·American Heart Journal·Syed Wamique YusufRadha A Mishra
Jul 27, 1996·Lancet·J French, H D White
Jan 6, 2005·American Heart Journal·Howard A CooperUNKNOWN Magnesium in Coronaries trial investigators
Feb 27, 2017·Pharmaceutical Research·Mafalda M DiasRoss A McKinnon
Mar 20, 2010·The Cochrane Database of Systematic Reviews·Brian S BuckleySusan M Smith
Dec 22, 2005·Proceedings·D L Glancy, B Khuri

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