PMID: 9420057Jan 7, 1998Paper

Selection of multiple-antibiotic-resistant (mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci

Antimicrobial Agents and Chemotherapy
M C MokenS B Levy

Abstract

Mutants of Escherichia coli selected for resistance to the disinfectant pine oil or to a household product containing pine oil also showed resistance to multiple antibiotics (tetracycline, ampicillin, chloramphenicol, and nalidixic acid) and overexpressed the marA gene. Likewise, antibiotic-selected Mar mutants, which also overexpress marA, were resistant to pine oil. Deletion of the mar or acrAB locus, the latter encoding a multidrug efflux pump positively regulated in part by MarA, increased the susceptibility of wild-type and mutant strains to pine oil.

References

Aug 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J T GreenbergB Demple
Mar 1, 1987·Microbiological Reviews·B R Lyon, R Skurray
Jul 1, 1982·Journal of Bacteriology·M S Curiale, S B Levy
Aug 25, 1995·Nucleic Acids Research·S K Goda, N P Minton
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·I T PaulsenR A Skurray
Jul 1, 1996·Antimicrobial Agents and Chemotherapy·K Maneewannakul, S B Levy
Oct 1, 1996·Journal of Bacteriology·H Nikaido
Dec 1, 1996·Microbiological Reviews·I T PaulsenR A Skurray

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Citations

Apr 15, 2003·Clinical Microbiology Reviews·Peter Gilbert, Andrew J McBain
Jan 14, 2004·Journal of Food Protection·Sherene S Golding, Karl R Matthews
Jul 23, 2004·The Journal of Antimicrobial Chemotherapy·L P RandallM J Woodward
Oct 14, 2004·Journal of Applied Microbiology·A H RickardP Gilbert
Sep 28, 2004·The Journal of Biological Chemistry·Steven P Wilkinson, Anne Grove
Apr 2, 2008·Biological & Pharmaceutical Bulletin·Dai-Wei LiTomofusa Tsuchiya
Mar 11, 2009·Journal of Medical Microbiology·Lucia Birosová, Mária Mikulásová
May 19, 2010·International Journal of Molecular Sciences·Jonas AnkarlooIan A Nicholls
Feb 26, 2016·Environmental Microbiology·Emmanuel KalilySima Yaron
Apr 6, 2018·Antimicrobial Resistance and Infection Control·Bothyna Ghanem, Randa Nayef Haddadin
Aug 7, 2019·Antimicrobial Agents and Chemotherapy·Alexandre TetardCatherine Llanes
Mar 22, 2005·Journal of Dairy Science·J M BurgosM F Varela
May 31, 2012·Antimicrobial Agents and Chemotherapy·Mark VelebaThamarai Schneiders
Aug 22, 2000·Antimicrobial Agents and Chemotherapy·K Poole
Oct 31, 2002·Applied and Environmental Microbiology·Christopher T D PriceJohn E Gustafson
Feb 28, 2001·Environmental Microbiology·A AlonsoJ L Martínez
Jul 5, 2005·Expert Opinion on Investigational Drugs·L E Lawrence, J F Barrett
Nov 18, 2006·Canadian Journal of Microbiology·Hua YangXiuping Jiang
Mar 7, 2001·Applied and Environmental Microbiology·L P Randall, M J Woodward
Oct 29, 2000·The Pediatric Infectious Disease Journal·S B Levy
May 9, 2002·Proceedings of the National Academy of Sciences of the United States of America·R T GillG Stephanopoulos
Sep 29, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·David J Weber, William A Rutala
Jan 1, 2013·International Journal of Bacteriology·Sanath KumarManuel F Varela
Jan 26, 2013·The Journal of Antimicrobial Chemotherapy·Mark VelebaThamarai Schneiders

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