PMID: 7014957Jun 26, 1981Paper

Selection of patients with chronic obstructive pulmonary disease for long-term oxygen therapy

JAMA : the Journal of the American Medical Association
R M TimmsG W Williams

Abstract

The Nocturnal Oxygen Therapy Trial, a study of oxygen therapy in patients with chronic obstructive pulmonary disease, has combined the experience of six centers concerning the selection of patients for oxygen treatment. Forty-five percent of hypoxic patients initially selected for the study improved enough during the one month of outpatient observation to allow suspension of plans to treat them with oxygen. Therefore, long-term oxygen therapy plans should only be made without a month of careful observation. Resting PaO2 values less than 40 mm Hg suggest instability or that chronic obstructive pulmonary disease is not the only cause of the hypoxemia. Nasal prong oxygen flow of 1 to 3 L/min reversed hypoxemia in 95% of stable patients with chronic obstructive pulmonary disease.

Citations

Dec 1, 1987·Controlled Clinical Trials·G W WilliamsD L DeMets
Nov 1, 1985·Thorax·T B Stretton
Jan 20, 2007·BMC Cardiovascular Disorders·Chandrashekhar D KamatMichael A Ihnat
Sep 27, 2012·Respiration; International Review of Thoracic Diseases·Florian F HildenbrandSilvia Ulrich
Dec 13, 2005·Treatments in Respiratory Medicine·Thomas J Ringbaek
Apr 15, 2015·Thorax·Maxine HardingeUNKNOWN British Thoracic Society Standards of Care Committee
Apr 30, 2017·Expert Review of Respiratory Medicine·F S MagnetW Windisch

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