PMID: 1034177Nov 1, 1976

Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. I. General procedures

Journal of Studies on Alcohol
E P RileyD Lester

Abstract

Strains of rats are being developed which have distinct responses in spontaneous locomotor activity to a subhypnotic dose of alcohol. The purpose is to produce one strain in which the injection of a standard dose of alcohol will result in objectively measurable intoxication and a second in which an identical dose will result in virtually no effect.

Citations

Jan 1, 1980·Psychopharmacology·N R Shapiro, E P Riley
Sep 1, 1979·Psychopharmacology·D H OverstreetM Messenger
Jan 1, 1982·Pharmacology, Biochemistry, and Behavior·L LumengT K Li
May 1, 1986·Pharmacology, Biochemistry, and Behavior·L A GruppR B Stewart
Dec 30, 2015·Journal of Nutrition and Metabolism·Shunji OshimaTomomasa Kanda
Oct 1, 1982·Biochemical Pharmacology·J M KhannaJ M Mayer
Jan 1, 1987·Psychopharmacology·E J GallaherJ C Crabbe
Jan 1, 1983·Alcoholism, Clinical and Experimental Research·D L AllenT K Nishimoto
Jan 1, 1988·The American Journal of Drug and Alcohol Abuse·L Tislenko, P Steinglass
Jan 1, 1978·The American Journal of Drug and Alcohol Abuse·S Johnson, S R Garzon
Jan 1, 1985·Social Biology·J R Wilson

Related Concepts

Ethanol
Alcoholic Intoxication
Alcohol Abuse
Breeding
Dose-Response Relationship, Drug
Injections, Intraperitoneal
Selection, Genetic

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.