PMID: 2511830Aug 1, 1989Paper

Selective epilepsy surgery in tuberous sclerosis

Australian Paediatric Journal
A M ByeR A Mackenzie

Abstract

A patient with tuberous sclerosis diagnosed at the age of 5 years developed an intractable seizure disorder characterized by complex partial seizures numbering 10-20/day. Interictal electroencephalograms (EEG) showed a right frontal epileptogenic focus. A computerized tomography scan demonstrated calcification in the right frontal region at two sites, periventricular calcification and multiple low density lesions. Neuropsychological assessment showed a verbal intelligence quotient (IQ) of 69 and a performance IQ of 88. Telemetry and video monitoring recorded 10 seizures during which the EEG showed flattening of ongoing sharp wave activity in the right frontal region. Electrocorticography further identified and localized epileptogenic tissue in the right frontal cortex and surgical removal of involved tissue and the adjacent two tubers was carried out. Twelve months after surgery the patient has had only two brief seizures.

References

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Citations

Apr 2, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Romina MoaveroPaolo Curatolo
May 9, 2007·Epilepsia·Floor E JansenOnno van Nieuwenhuizen
Oct 7, 2004·Pediatric Neurology·Pantaleo RomanelliPaolo Curatolo
Apr 7, 2007·Seizure : the Journal of the British Epilepsy Association·F E JansenUNKNOWN Dutch Collaborative Epilepsy Surgery Programme
Jan 1, 1992·Journal of Child Neurology·L Nagarajan, A M Bye
Oct 17, 2015·Journal of Child Neurology·Benjamin M EllingsonNoriko Salamon
Jan 1, 1997·Journal of Child Neurology·P J Rintahaka, H T Chugani
Dec 31, 2002·Journal of Child Neurology·Pantaleo RomanelliOrrin Devinsky
Apr 5, 2011·Journal of Neurosurgery. Pediatrics·Chad CarlsonHoward L Weiner
Sep 1, 1997·Journal of Neurosurgery·A M AvellinoG A Ojemann
Mar 3, 2012·Neurosurgical Focus·Linton T EvansDavid W Roberts
Sep 2, 2008·Neurosurgical Focus·Robert J BolloHoward L Weiner
Jul 1, 1993·Epilepsia·E M BebinM R Gomez
May 1, 1994·Epilepsia·A M Bye, S Foo
Jan 1, 1993·The Psychiatric Quarterly·J C ChouE A Sweeney
Jan 1, 1991·Annals of the New York Academy of Sciences·P CuratoloO Dulac
Sep 27, 2014·International Journal of Dermatology·Federica DassoniValeska Padovese

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