PMID: 19912900Dec 1, 1992Paper

Selective expression of peripherin in gonadotropin-releasing hormone-synthesizing neurons of the rat

Molecular and Cellular Neurosciences
L Jennes

Abstract

Immunofluorescent double stainings for gonadotropin-releasing hormone (GnRH) and peripherin, vimentin, or neurofilament-70 were used to determine the identity of the intermediate filaments in GnRH neurons of the adult rat. The results show that GnRH cells are unique neurons in the septum-rostral hypothalamus in that they express peripherin and vimentin but not neurofilament-70. Both peripherin and vimentin form a dense perinuclear network from which peripherin extends only into the proximal neurites, while vimentin can be seen in certain GnRH terminals in the median eminence. The presence of peripherin and vimentin in GnRH neurons as well as in olfactory receptor neurons suggests close ties between these cell types and supports the view that both cell types arise from a common ancestor.

References

Oct 1, 1991·The Journal of Steroid Biochemistry and Molecular Biology·M Schwanzel-Fukuda, D W Pfaff
Dec 15, 1990·Brain Research. Developmental Brain Research·J D GorhamE B Ziff
Feb 23, 1990·Cell·P M Steinert, R K Liem
Jun 1, 1989·Trends in Neurosciences·L A Greene
Mar 9, 1989·Nature·M Schwanzel-Fukuda, D W Pfaff
Jan 1, 1988·Annual Review of Biochemistry·P M Steinert, D R Roop
Jul 1, 1987·The Journal of Cell Biology·S D Georgatos, G Blobel
Jan 1, 1988·The Journal of Cell Biology·D G LeonardE B Ziff
Sep 1, 1987·Molecular and Cellular Biology·D G LeonardL A Greene
Feb 22, 1985·The Journal of Comparative Neurology·L JennesM E Sheedy
Jan 1, 1983·Developmental Neuroscience·M M PortierF Gros

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Citations

Aug 1, 1995·Molecular Reproduction and Development·J BradshawR M Moor
Sep 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·P SharmaH C Pant

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