Selective identification of different brachytherapy sources, ferromagnetic seeds, and fiducials in the prostate using an automated seed sorting algorithm

Brachytherapy
Brian J DavisRobert W Kline

Abstract

Routine permanent prostate brachytherapy (PPB) includes CT-based postimplant dosimetry (PID). A method of identifying different source types from CT data in the same implant volume is described. A previously described automatic method for seed localization using CT data is used in this study. Two cases were analyzed: a PPB case with (103)Pd followed by salvage (125)I implantation, both performed at another institution, and a cadaver case where 4 different seed types, including ferromagnetic seeds, and fiducials were implanted. Automatic segregation of different seed types with minimal manual correction is demonstrated using the described localization algorithm. The process is confirmed accurate by comparison of plain film radiographs to CT data and digitally reconstructed radiographs. Unique identification of different source types, including PPB seeds, fiducial markers, and ferromagnetic seeds in permanent implants is possible and permits dosimetric analyses that are spatially coincident.

References

Mar 1, 1992·Medical Physics·A S MeigooniR Nath
Oct 6, 1997·International Journal of Radiation Oncology, Biology, Physics·J Willins, K Wallner
Apr 8, 1998·International Journal of Radiation Oncology, Biology, Physics·J J PreteP D Grimm
May 20, 1998·International Journal of Radiation Oncology, Biology, Physics·R G StockJ K DeWyngaert
Oct 17, 1998·Medical Physics·D H Brinkmann, R W Kline
Jul 1, 1999·International Journal of Radiation Oncology, Biology, Physics·S NagR Nath
Mar 8, 2000·International Journal of Radiation Oncology, Biology, Physics·J C BlaskoW Cavanagh
Jan 9, 2001·CA: a Cancer Journal for Clinicians·H RagdeA A Elgamal
Apr 18, 2002·International Journal of Radiation Oncology, Biology, Physics·Jose L Garcia-RamirezJames A Purdy
Sep 24, 2002·International Journal of Radiation Oncology, Biology, Physics·W Robert LeeDavid Beyer

❮ Previous
Next ❯

Citations

Apr 25, 2007·Journal of Biomedical Materials Research. Part a·Abdel Kareem AzabAbraham Rubinstein
Feb 28, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·Abdel Kareem AzabAbraham Rubinstein

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.