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Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow

British Journal of Clinical Pharmacology

Jan 1, 1983

J HarlanL Harker

Abstract

1 The effects of a selective thromboxane synthetase inhibitor, dazoxiben (UK 37248), on haemodynamics, eicosanoid levels, and lung vascular permeability were assessed in three unanesthetized goats with chronic lung lymph fistulae following infusions of E. coli endotoxin (1 microgram/kg)...read more

Mentioned in this Paper

Thromboxane A2
Pulmonary Edema
Prostaglandin F1 Alpha Measurement
Dazoxiben
Endotoxemia
Alkalescens-Dispar Group
Lung
Tang Hsi Ryu Syndrome
Oxidase
Inhibitors
Paper Details
References
  • References2
  • Citations8
  • References2
  • Citations8
1

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Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow

British Journal of Clinical Pharmacology

Jan 1, 1983

J HarlanL Harker

PMID: 6337602

DOI: 10.1111/j.1365-2125.1983.tb02122.x

Abstract

1 The effects of a selective thromboxane synthetase inhibitor, dazoxiben (UK 37248), on haemodynamics, eicosanoid levels, and lung vascular permeability were assessed in three unanesthetized goats with chronic lung lymph fistulae following infusions of E. coli endotoxin (1 microgram/kg)...read more

Mentioned in this Paper

Thromboxane A2
Pulmonary Edema
Prostaglandin F1 Alpha Measurement
Dazoxiben
Endotoxemia
Alkalescens-Dispar Group
Lung
Tang Hsi Ryu Syndrome
Oxidase
Inhibitors

Feeds With Similar Papers

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

The Journal of Clinical Investigation

Thromboxane A2 mediates lung vasoconstriction but not permeability after endotoxin

The Journal of Clinical InvestigationSeptember 1, 1983
R WinnJ Hildebrandt
Paper Details
References
  • References2
  • Citations8
  • References2
  • Citations8
1

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